merck millipore,默克密理博,537009,Progranulin, CF, Mouse, Recombinant

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merck millipore,默克密理博,537009,Progranulin, CF, Mouse, Recombinant
产品名称：Progranulin, CF, Mouse, Recombinant
产品型号：537009

merck millipore,默克密理博,537009,Progranulin, CF, Mouse, Recombinant

产品介绍

merck millipore,默克密理博,537009,Progranulin, CF, Mouse, Recombinant

重要规格表

纯度
≥90% by SDS-PAGE

描述
概述	Recombinant, mouse progranulin, consisting of amino acids 18-589, fused at the C-terminus to a His•Tag^® sequence, and expressed in NS0-derived mouse myeloma cells. Progranulin is an ubiquitously expressed, secreted glycoprotein that is involved in regulation of cell proliferation.
产品目录编号	537009
品牌系列	Calbiochem®
同义词	PC cell-derived growth factor (PCDGF)

参考
参考	Liu, Y. et al. 2007. BMC Cancer 7, 22. Xu, K. et al. 2007. J. Biol. Chem. 282, 11347. Barreda, D.R. et al. 2004. Dev. Comp. Immunol. 28, 727. Davidson, B. et al. 2004. Cancer 100, 2139. Sun, X. et al. 2004. Am. J. Respir. Cell Mol. Biol. 30, 510. Gonzalez, E.M. et al. 2003. J. Biol. Chem. 278, 38113. He, Z. et al. 2003. Nat. Med. 9, 225. He, Z. and Bateman, A. 2003. J. Mol. Med. 81, 600. Jones, M.B. et al. 2003. Gynecol. Oncol. 88, S136. Wang, W. et al. 2003. Clin. Cancer Res. 9, 2221. Suzuki, M. and Nishiahara, M. 2002. Mol. Genet. Metab. 75, 31. Zhu, J. et al. 2002. Cell 111, 867. Lu, R. and Serrero, G. 2000. Proc. Natl. Acad. Sci. U.S.A. 97, 3993. Justen, H.P. et al. 2000. Mol. Cell Biol. Res. Commun. 3, 165. Zanocco Marani, T. et al. 1999. Cancer Res. 59, 5331. Zhang, H. and G. Serrero 1998. Proc. Natl. Acad. Sci. U.S.A. 95, 14202. Zhou, J. et al. 1993. J. Biol. Chem. 268, 10863. Plowman, G.D. et al. 1992. J. Biol. Chem. 267, 13073. Bateman, A. et al. 1990. Biochem. Biophys. Res. Commun. 173, 1161.

参考

Liu, Y. et al. 2007. BMC Cancer 7, 22.
Xu, K. et al. 2007. J. Biol. Chem. 282, 11347.
Barreda, D.R. et al. 2004. Dev. Comp. Immunol. 28, 727.
Davidson, B. et al. 2004. Cancer 100, 2139.
Sun, X. et al. 2004. Am. J. Respir. Cell Mol. Biol. 30, 510.
Gonzalez, E.M. et al. 2003. J. Biol. Chem. 278, 38113.
He, Z. et al. 2003. Nat. Med. 9, 225.
He, Z. and Bateman, A. 2003. J. Mol. Med. 81, 600.
Jones, M.B. et al. 2003. Gynecol. Oncol. 88, S136.
Wang, W. et al. 2003. Clin. Cancer Res. 9, 2221.
Suzuki, M. and Nishiahara, M. 2002. Mol. Genet. Metab. 75, 31.
Zhu, J. et al. 2002. Cell 111, 867.
Lu, R. and Serrero, G. 2000. Proc. Natl. Acad. Sci. U.S.A. 97, 3993.
Justen, H.P. et al. 2000. Mol. Cell Biol. Res. Commun. 3, 165.
Zanocco Marani, T. et al. 1999. Cancer Res. 59, 5331.
Zhang, H. and G. Serrero 1998. Proc. Natl. Acad. Sci. U.S.A. 95, 14202.
Zhou, J. et al. 1993. J. Biol. Chem. 268, 10863.
Plowman, G.D. et al. 1992. J. Biol. Chem. 267, 13073.
Bateman, A. et al. 1990. Biochem. Biophys. Res. Commun. 173, 1161.

产品信息
形式	Lyophilized
配方	Lyophilized from 0.2 µm filtered PBS.
Molar Mass	62400

生物信息
生物活性	Significantly enhances neurite outgrowth of E18 rat embryonic cortical neurons using 4-16 µg/ml progranulin immobilized on nitrocelluose-coated microplates.
纯度	≥90% by SDS-PAGE

理化信息
污染物	Endotoxin: ≤1.0 EU/µg protein
溶解度	PBS

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	-20°C
无需冷冻	No
特殊指南	Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.