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merck millipore,默克密理博,528245,PLD Inhibitor, FIPI - Calbiochem
产品名称：PLD Inhibitor, FIPI - Calbiochem
产品型号：528245
The PLD Inhibitor, FIPI controls the biological activity of PLD. This small molecule/inhibitor is primarily used for Membrane applications.
merck millipore,默克密理博,528245,PLD Inhibitor, FIPI - Calbiochem
- 产品介绍
重要规格表
经验配方 C₂₃H₂₄FN₅O₂ 描述 概述 A cell-permeable, PLD1/2 inhibitor (IC50 = 1 nM and 10 nM for PLD1 and PLD2, respectively, in a CHO cell based assay, and IC50 = 20 nM for PLD2 in a biochemical assay), that displays no activity toward MitoPLD, and is selective for PLD1 and PLD2 over other PLD superfamily enzymes. It is also shown to block PLD2-dependent effects on cytoskeletal reorganization and cell trafficking in CHO cells, and diminish fMLP-directed neutrophil chemotaxis in HL60 cells at 750 nM. Unlike 1-butanol, this compound does not affect glucose-stimulated insulin secretion in Min6 pancreatic β-cells. 产品目录编号 528245 品牌系列 Calbiochem®
同义词 Compound 4k, PLD Inhibitor I 参考 参考 Su, W., et al. 2009. Mol Pharmacol 75, 437.
Monovich, L., et al. 2007. Bioorg Med Chem 17, 2310.产品信息 形式 Off-white powder Hill配方 C₂₃H₂₄FN₅O₂ 化学配方 C₂₃H₂₄FN₅O₂ Molar Mass 421.19 结构配方图像 生物信息 纯度 ≥99% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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下一件merck millipore产品：merck millipore,默克密理博,196440,Batimastat - CAS 130370-60-4 - Calbiochem
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