merck millipore,默克密理博,524644,L-α-Phosphatidyl-D-myo-inositol-4,5-bisphosphate, Triammonium Salt, Porcine Brain - CAS 383907-42-4

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

当前位置：首页 > >Merck Millipore > 生命科学研究
生命科学研究

merck millipore,默克密理博,524644,L-α-Phosphatidyl-D-myo-inositol-4,5-bisphosphate, Triammonium Salt, Porcine Brain - CAS 383907-42-4 - Calbiochem
产品名称：L-α-Phosphatidyl-D-myo-inositol-4,5-bisphosphate, Triammonium Salt, Porcine Brain - CAS 383907-42-4 - Calbiochem
产品型号：524644
A component of membrane-bound receptors in association with phospholipase C (PLC).

merck millipore,默克密理博,524644,L-α-Phosphatidyl-D-myo-inositol-4,5-bisphosphate, Triammonium Salt, Porcine Brain - CAS 383907-42-4 - Calbiochem

产品介绍

merck millipore,默克密理博,524644,L-α-Phosphatidyl-D-myo-inositol-4,5-bisphosphate, Triammonium Salt, Porcine Brain - CAS 383907-42-4 - Calbiochem

重要规格表

经验配方	CAS号
C₄₇H₈₂O₁₉P₃ · 3NH₄	383907-42-4

描述
概述	A component of membrane-bound receptors in association with phospholipase C (PLC). Potently stimulates brain phospholipase D (PLD) activity in vitro. Has been shown to activate protein kinase C (PKC) in the presence of phosphatidylserine and Ca²⁺. Antagonist of ATP-sensitive potassium (K_ATP) channels when applied to inside-out membrane patches.
产品目录编号	524644
品牌系列	Calbiochem®
同义词	PIP₂

参考
参考	Baukrowitz, T., et al. 1998. Science 282, 1141. Shyng, S.-L., and Nichols, C.G. 1998. Science 282, 1138. Mazzotti, G., et al. 1995. J. Histochem. Cytochem. 43, 181. Liscovitch, M., et al. 1994. J. Biol. Chem. 269, 21403. Chauhan, A., et al. 1991. Biochem. Biophys. Res. Commun. 175, 852. Williamson, J.R. 1986. Hypertension 8, 140. Berridge, M.J., and Irvine, R.F. 1984. Nature 312, 315.

参考

Baukrowitz, T., et al. 1998. Science 282, 1141.
Shyng, S.-L., and Nichols, C.G. 1998. Science 282, 1138.
Mazzotti, G., et al. 1995. J. Histochem. Cytochem. 43, 181.
Liscovitch, M., et al. 1994. J. Biol. Chem. 269, 21403.
Chauhan, A., et al. 1991. Biochem. Biophys. Res. Commun. 175, 852.
Williamson, J.R. 1986. Hypertension 8, 140.
Berridge, M.J., and Irvine, R.F. 1984. Nature 312, 315.

产品信息
CAS号	383907-42-4
具有ATP竞争性	N
形式	White to off-white solid
Hill配方	C₄₇H₈₂O₁₉P₃ · 3NH₄
化学配方	C₄₇H₈₂O₁₉P₃ · 3NH₄
Molar Mass	1096.4
吸湿	Hygroscopic
可逆	N
结构配方图像

生物信息
主靶	Brain phospholipase D (PLD)
纯度	≥98% by TLC

理化信息
细胞可渗透	N
溶解度	Chloroform or H₂O

安全信息
R相	R: 36/37/38 Irritating to eyes, respiratory system and skin.
S相	S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

储存和货运信息
货运代码	Dry Ice Only
毒性	Irritant
储存	≤ -70°C
避光	Protect from light
吸湿	Hygroscopic
无需冷冻	No
特殊指南	Following reconstitution in H₂O, store in the refrigerator (4°C). Do not freeze aqueous solutions. Following reconstitution in chloroform, aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 2 days at 4°C. Chloroform stock solutions are stable for up to 1 month at -20°C.