• merck millipore,默克密理博,524390,Phorbol-12,13-dibutyrate - CAS 37558-16-0 - Calbiochem
  • merck millipore,默克密理博,524390,Phorbol-12,13-dibutyrate - CAS 37558-16-0 - Calbiochem

    产品名称:Phorbol-12,13-dibutyrate - CAS 37558-16-0 - Calbiochem
    产品型号:524390
    Strong irritant for mouse skin, but only moderately active as a tumor promoter.

    merck millipore,默克密理博,524390,Phorbol-12,13-dibutyrate - CAS 37558-16-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,524390,Phorbol-12,13-dibutyrate - CAS 37558-16-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₈H₄₀O₈37558-16-0
    描述
    概述 Strong irritant for mouse skin, but only moderately active as a tumor promoter. Activates protein kinase C. Stimulates the phosphorylation of Na+,K+- ATPase, thereby inhibiting its activity. Promotes the expression of inducible NOS in cultured hepatocytes. Commonly used in binding studies or in applications requiring high concentrations of phorbol compounds.
    产品目录编号 524390
    品牌系列 Calbiochem®
    同义词 PDBu, PKC Activator II
    参考
    参考 Fisone, G., et al. 1995. J. Biol. Chem. 270, 2427.
    Lee, E.J., et al. 1994. Brain Res. 665, 127.
    Critz, S.D., et al. 1993. J. Neurochem. 60, 1175.
    Iredale, P.A., et al. 1993. Biochem. Pharmacol. 45, 611.
    Critz, S.D., and Byrne J.H. 1992. J. Neurophys. 68, 1079.
    Hortelano, S., et al. 1992. J. Biol. Chem. 267, 24937.
    Ward C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol. 24, 937.
    产品信息
    CAS号 37558-16-0
    具有ATP竞争性 N
    形式 Clear film or white crystalline solid
    Hill配方 C₂₈H₄₀O₈
    化学配方 C₂₈H₄₀O₈
    Molar Mass 504.6
    可逆 N
    结构配方图像
    生物信息
    主靶 Na+,K+- ATPase
    纯度 ≥99% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    GHS安全信息
    RTECS EK7767000
    安全信息
    R相 R: 26/27/28-36/37/38-40-41

    Very toxic by inhalation, in contact with skin and if swallowed.
    Irritating to eyes, respiratory system and skin.
    Limited evidence of a carcinogenic effect.
    Risk of serious damage to eyes.
    S相 S: 26-36/37/39-45

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing, gloves and eye/face protection.
    In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Highly Toxic & Carcinogenic / Teratogenic
    有害材料注意事项: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
    储存 -20°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). DMSO stock solutions are stable for up to 6 months at -20°C. With frequent use, the DMSO stock solutions may accumulate water. The presence of water in the stock solution will accelerate the decomposition of the product, resulting in significant loss of activity in 2-3 months.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,524390,Phorbol-12,13-dibutyrate - CAS 37558-16-0 - Calbiochem

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