merck millipore,默克密理博,512732,Parthenolide, Tanacetum parthenium - CAS 20554-84-1

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Merck Millipore 默克密理愽

merck millipore,默克密理博,512732,Parthenolide, Tanacetum parthenium - CAS 20554-84-1 - Calbiochem

经验配方	CAS号
C₁₅H₂₀O₃	20554-84-1

描述
概述	A cell-permeable sesquiterpene lactone with anti-inflammatory, antisecretory, and spasmolytic properties. Inhibits the expression of COX-2 and proinflammatory cytokines (TNF-α and IL-1) in LPS-stimulated macrophages. Also inhibits NF-κB and activation of MAP kinase.
产品目录编号	512732
品牌系列	Calbiochem®

参考
参考	Wong, H.R., et al. 1999. Biochem. Biophys. Res. Comm.262, 375. Bork, P.M., et al. 1997. FEBS Lett. 402, 85. Hwang, D., et al. 1996. Biochem. Biophys. Res. Commun. 226, 810. Barsby, R.W., et al. 1992. J. Pharm. Pharmacol. 44, 737. Sumner, H., et al. 1992. Biochem. Pharmacol. 43, 2313.

生物信息
主靶	the expression of COX-2 and proinflammatory cytokines (TNF-α and IL-1) in LPS-stimulated macrophages
纯度	≥97% by TLC

理化信息
细胞可渗透	Y
溶解度	DMSO or EtOH

GHS安全信息
RTECS	LY4220000

安全信息
R相	R: 20/21/22-40-42/43 Harmful by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. May cause sensitization by inhalation and skin contact.
S相	S: 22-36 Do not breathe dust. Wear suitable protective clothing.

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Harmful & Carcinogenic / Teratogenic
储存	-20°C
避光	Protect from light
无需冷冻	No
特殊指南	Following initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

包装信息
惰性气体下包装	Packaged under inert gas

merck millipore,默克密理博,512732,Parthenolide, Tanacetum parthenium - CAS 20554-84-1 - Calbiochem

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