merck millipore,默克密理愽
  • merck millipore,默克密理博,506134,Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem

  • merck millipore,默克密理博,506134,Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem

    产品名称：Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem
    产品型号：506134
    A cell-permeable and very stable analog of Pifithrin-α with similar biological function, but with reduced cytotoxicity.

    merck millipore,默克密理博,506134,Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,506134,Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆H₁₆N₂S · HBr60477-34-1
    描述
    概述 A cell-permeable and very stable analog of Pifithrin-α (Cat. No. 506132), with similar biological function, but with reduced cytotoxicity. A chemical inhibitor of p53. Reversibly inhibits p53-dependent transactivation of p53-responsive genes; also reversibly blocks p53-mediated apoptosis. Acts as a P-gp modulator by changing relative substrate specificity of the transporter. This compound has been reported to be a potent STAT6 transcriptional inhibitor.
    产品目录编号 506134
    品牌系列 Calbiochem®
    同义词 2-(4-Methylphenyl)imidazo[2,1-b]-5,6,7,8-tetrahydrobenzothiazole, HBr, QB102, Pifithrin-β, PFTβ
    参考
    参考 Walton, M.I., et al. 2005. Mol. Cancer Ther. 4, 1369.
    Kondratov, R.V., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 14078.
    产品信息
    CAS号 60477-34-1
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₁₆H₁₆N₂S · HBr
    化学配方 C₁₆H₁₆N₂S · HBr
    Molar Mass 349.3
    可逆 Y
    结构配方图像
    生物信息
    主靶 PS3
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    防潮 Protect from moisture
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,506134,Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,SF-1431,CGRPA; Rat, Cyanine 3 RNA Detection Probe,SmartFlare


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