merck millipore,默克密理博,487960,Nociceptin - CAS 170713-75-4

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

merck millipore,默克密理博,487960,Nociceptin - CAS 170713-75-4 - Calbiochem

经验配方	CAS号
C₇₉H₁₂₉N₂₇O₂₂	170713-75-4

描述
概述	Endogenous ligand for the opioid-like G-protein coupled receptor, ORL1 (Opioid Receptor-Like 1). Has no significant activity on the µ, δ, or κ opioid receptors; however, nanomolar concentrations of nociceptin inhibit forskolin-stimulated adenylyl cyclase activity in cells transfected with the G-protein coupled receptor LC132, which is similar in sequence to the opioid receptor. Also reported to cause hypertension and bradycardia in mice.
产品目录编号	487960
品牌系列	Calbiochem®
同义词	Orphanin FQ, OFQ, NC, FGGFTGARKSARKLANQ

参考
参考	Madeddu, P., et al. 1999. Hypertension 33, 914. Sandin, J., et al. 1999. NeuroReport 10, 71. Meunier, J., et al. 1995. Nature 377, 532. Reinscheid, R.K., et al. 1995. Science 270, 792.

产品信息
CAS号	170713-75-4
具有ATP竞争性	N
形式	White lyophilized solid
配方	Supplied as a trifluoroacetate salt.
Hill配方	C₇₉H₁₂₉N₂₇O₂₂
化学配方	C₇₉H₁₂₉N₂₇O₂₂
Molar Mass	1809.1
吸湿	Hygroscopic
肽序列	H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Leu-Ala-Asn-Gln-OH
可逆	N

生物信息
主靶	Opioid-like G-protein coupled receptor, ORL1 (Opioid Receptor-Like 1)
纯度	≥98% by HPLC

理化信息
细胞可渗透	N
溶解度	H₂O
肽序列	H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Leu-Ala-Asn-Gln-OH

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	-20°C
吸湿	Hygroscopic
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions.

merck millipore,默克密理博,487960,Nociceptin - CAS 170713-75-4 - Calbiochem

whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech