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merck millipore,默克密理博,474700,Mevastatin - CAS 73573-88-3 - Calbiochem
产品名称：Mevastatin - CAS 73573-88-3 - Calbiochem
产品型号：474700
An antibiotic that acts as a potent inhibitor of HMG-CoA reductase, thus suppressing Ras farnesylation.
merck millipore,默克密理博,474700,Mevastatin - CAS 73573-88-3 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₂₃H₃₄O₅ 73573-88-3 描述 概述 An antibiotic that acts as a potent inhibitor of HMG-CoA reductase, thus suppressing Ras farnesylation. Inhibitor of myoblast fusion. Also may induce bone morphogenic protein-2 (BMP-2). Causes cell cycle arrest in late G1 phase. This is an inactive form which may require activation for use with isolated cells depending upon the application. To activate, treat with NaOH in ethanol and then neutralize to pH 7.2. 产品目录编号 474700 品牌系列 Calbiochem®
同义词 Compactin 参考 参考 Sugiyama, M., et al. 2000. Biochem. Biophys. Res. Commun. 271, 688.
Hug, T., et al. 1995. Pflugers Archiv. Eur. J. Physiol. 429, 682.
Belo, R.S., et al. 1993. Mol. Cell. Biochem. 126, 159.
McLeish, K.R., et al. 1993. Biochem. Biophys. Res. Commun. 197, 763.
Keyomarsi, K., et al. 1991. Cancer Res. 51, 3602.
Jackson, J.H., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 3042.
Kita, T., et al. 1980. J. Clin. Invest. 66, 1094.产品信息 CAS号 73573-88-3 具有ATP竞争性 N 形式 White solid Hill配方 C₂₃H₃₄O₅ 化学配方 C₂₃H₃₄O₅ Molar Mass 390.5 可逆 N 结构配方图像 生物信息 主靶 HMG-CoA reductase 纯度 ≥95% by HPLC 理化信息 细胞可渗透 N 溶解度 EtOH GHS安全信息 RTECS EK7907100 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
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