merck millipore,默克密理愽
  • merck millipore,默克密理博,46-692MAG,MILLIPLEX MAP Phospho H2A.X (Ser139) Magnetic Bead MAPmate- Cell Signaling Single Plex

  • merck millipore,默克密理博,46-692MAG,MILLIPLEX MAP Phospho H2A.X (Ser139) Magnetic Bead MAPmate- Cell Signaling Single Plex

    产品名称：MILLIPLEX MAP Phospho H2A.X (Ser139) Magnetic Bead MAPmate- Cell Signaling Single Plex
    产品型号：46-692MAG
    MILLIPLEX MAP Phospho H2A.X (Ser139) Magnetic Bead MAPmate, 46-692MAG- Cell Signaling Single Plex. The analyte available for this kit is H2A.X (Ser139).

    merck millipore,默克密理博,46-692MAG,MILLIPLEX MAP Phospho H2A.X (Ser139) Magnetic Bead MAPmate- Cell Signaling Single Plex

  • 产品介绍
  • merck millipore,默克密理博,46-692MAG,MILLIPLEX MAP Phospho H2A.X (Ser139) Magnetic Bead MAPmate- Cell Signaling Single Plex

    重要规格表

    可用的分析物 品种反应性 主要应用 检测方法
    H2A.X (Ser139)M, HMplexLuminex xMAP
    描述
    产品目录编号 46-692MAG
    商名
    • MILLIPLEX
    描述 MILLIPLEX MAP Phospho H2A.X (Ser139) Magnetic Bead MAPmate- Cell Signaling Single Plex
    背景信息 H2A.X
    • Involved in gene regulation and chromatin packaging
    • H2A is a core histone which multimerizes with other histones
    • The C-terminus of H2A.X is involved with DNA repair
    产品信息
    检测方法 Luminex xMAP
    配置 Single Plex
    板面类型 Cell Signaling
    应用
    应用 MILLIPLEX MAP Phospho H2A.X (Ser139) Magnetic Bead MAPmate, 46-692MAG- Cell Signaling Single Plex. The analyte available for this kit is H2A.X (Ser139).
    主要应用
    • Multiplexing
    应用说明 • An overnight (4°C) incubation is recommended for best results
    • These assays require 25 µL diluted cell lysate per well
    • Please consult the buffer compatibility chart or protocol for appropriate buffer choice
    • 1 - 25 μg cell lysate/well (recommended starting concentration is 20 μg)
    生物信息
    品种反应性 MouseHuman
    可用的分析物
    • H2A.X (Ser139)
    Entrez基因编号
    • NM_002105
    Entrez基因汇总 Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif
    修改
    • Phosphorylation
    UniProt编号
    • P27661
    UniProt汇总 [FUNCTION] Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Recommended storage for kit components is 2 - 8°C
    包装信息
    数量 96-well plate

    merck millipore,默克密理博,46-692MAG,MILLIPLEX MAP Phospho H2A.X (Ser139) Magnetic Bead MAPmate- Cell Signaling Single Plex

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