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merck millipore,默克密理博,445888,Metastin (45-54) - Calbiochem
产品名称：Metastin (45-54) - Calbiochem
产品型号：445888
A decapeptide with C-terminally amidated LRF-motif that acts as a potent and selective agonist of AXOR12 and hOT7T175 (a novel human G-protein-coupled receptors).
merck millipore,默克密理博,445888,Metastin (45-54) - Calbiochem
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经验配方 C₆₃H₈₃N₁₇O₁₄ 描述 概述 A decapeptide with C-terminally amidated LRF-motif that acts as a potent and selective agonist of AXOR12 and hOT7T175 (a novel human G-protein-coupled receptors). Induces an increase in intracellular Ca2+ levels in CHO/h175 and CHO/AXOR12:Gqi5 cells and exhibits about 8-fold higher receptor binding affinity (Ki = 42 pM) compared to Metastin (Cat. No. 445885). 产品目录编号 445888 品牌系列 Calbiochem®
同义词 KiSS-1 (112-121), Kisspeptin-10, H-YNWNSFGLRF-NH₂ 参考 参考 Kotani, M., et al. 2001. J. Biol. Chem. 276, 34631.
Ohtaki, T., et al. 2001. Nature 411, 613.
Muir, A.I., et al. 2001. J. Biol. Chem. 276, 28969.产品信息 具有ATP竞争性 N 形式 White lyophilized solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₆₃H₈₃N₁₇O₁₄ 化学配方 C₆₃H₈₃N₁₇O₁₄ Molar Mass 1302.5 吸湿 Hygroscopic
肽序列 H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂ 可逆 N 生物信息 主靶 AXOR12 and hOT7T175 主靶Ki 42 pM for AXOR12 and hOT7T175 纯度 ≥97% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO 肽序列 H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂ 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 1 month at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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