merck millipore,默克密理愽
  • merck millipore,默克密理博,444288,MMP-2 Inhibitor III - CAS 704888-90-4 - Calbiochem

  • merck millipore,默克密理博,444288,MMP-2 Inhibitor III - CAS 704888-90-4 - Calbiochem

    产品名称：MMP-2 Inhibitor III - CAS 704888-90-4 - Calbiochem
    产品型号：444288
    The MMP-2 Inhibitor III, also referenced under CAS 704888-90-4, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

    merck millipore,默克密理博,444288,MMP-2 Inhibitor III - CAS 704888-90-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,444288,MMP-2 Inhibitor III - CAS 704888-90-4 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₇H₂₀N₂O₅S704888-90-4
    描述
    概述 A cell-permeable biphenylsulfonamido-hydroxamate compound that acts a potent and Zn2+-binding site-targeting inhibitor of MMP-2 (IC50 = 12 nM). It exhibits good selectivity over MMP-9 and MMP-3 (IC50 = 0.2 and 4.5 µM, respectively) and shows practically no effect towards MMP-1 and MMP-7 (IC50 > 50 µM). Shown to effectively suppress the invasiveness of HT1080 sarcoma cells grown on matrigel.
    产品目录编号 444288
    品牌系列 Calbiochem®
    同义词 (2-((Isopropoxy)-(1,1ʹ-biphenyl-4-ylsulfonyl)-amino))-N-hydroxyacetamide
    参考
    参考 Tuccinardi, T., et al. 2006. Bioorg. Med. Chem. 14, 4260.
    Rossello, A., et al. 2004. Bioorg. Med. Chem. 12, 2441.
    产品信息
    CAS号 704888-90-4
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₁₇H₂₀N₂O₅S
    化学配方 C₁₇H₂₀N₂O₅S
    Molar Mass 364.4
    可逆 N
    结构配方图像
    生物信息
    主靶 MMP-2
    主靶IC50 12 nM against MMP-2
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or MeOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,444288,MMP-2 Inhibitor III - CAS 704888-90-4 - Calbiochem

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