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merck millipore,默克密理博,444282,MMP/TACE Substrate, FS-6 - Calbiochem
产品名称:MMP/TACE Substrate, FS-6 - Calbiochem
产品型号:444282
The widely used MMP substrate FS-1 is modified by an N-terminal lysine elongation to produce a broad-spectrum MMP and TACE substrate that displays improved water solubility and substrate sensitivities More>>
merck millipore,默克密理博,444282,MMP/TACE Substrate, FS-6 - Calbiochem
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重要规格表
描述 概述 The widely used MMP substrate FS-1 (Cat. No. 03-32-5032) is modified by an N-terminal lysine elongation to produce a broad-spectrum MMP and TACE substrate that displays improved water solubility and substrate sensitivities. Exhibits 2- to 9-fold higher specificity constant (kcat/Km) towards MMP-1, -8, -13, -14 when compared with FS-1 and ~2-fold higher kcat/Km towards TACE when compared with TACE Substrate II and III (Cat. Nos. 616402 and 616403, respectively). It has been used successfully in detecting T98G glioma cell surface-associated MMP activity and is shown to be resistant to proteolysis by human leukocyte elastase, trypsin, and ADAM-10. 产品目录编号 444282 品牌系列 Calbiochem®
同义词 Mca-KPLG~L-Dpa-AR-NH₂ 参考 参考 Neumann, U., et al. 2004. Anal. Biochem. 328, 166. 产品信息 具有ATP竞争性 N 形式 Lyophilized 配方 Supplied as a trifluoroacetate salt. Hill配方 C₅₅H₈₀N₁₆O₁₆ 化学配方 C₅₅H₈₀N₁₆O₁₆ Molar Mass 1221.3 吸湿 Hygroscopic
肽序列 Mca-Lys-Pro-Leu-Gly~Leu-Dpa-Ala-Arg-NH₂ 可逆 N 生物信息 主靶 Broad-spectrum MMP and TACE substrate 纯度 ≥97% by HPLC 理化信息 细胞可渗透 N 溶解度 H₂O or 5% Acetic Acid 肽序列 Mca-Lys-Pro-Leu-Gly~Leu-Dpa-Ala-Arg-NH₂ 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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