merck millipore,默克密理愽
  • merck millipore,默克密理博,438210,LSF Inhibitor, FQI1 - Calbiochem

  • merck millipore,默克密理博,438210,LSF Inhibitor, FQI1 - Calbiochem

    产品名称：LSF Inhibitor, FQI1 - Calbiochem
    产品型号：438210
    The LSF Inhibitor, FQI1 controls the biological activity of LSF.

    merck millipore,默克密理博,438210,LSF Inhibitor, FQI1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,438210,LSF Inhibitor, FQI1 - Calbiochem

    重要规格表

    经验配方
    C₁₈H₁₇NO₄
    描述
    概述 A cell-permeable dihydroquinolinone compound that acts as a potent, specific, and reversible inhibitor of DNA-binding activity of Late SV40 Factor (LSF) and blocks LSF transactivation (IC50 = 2.1 µM in NIH 3T3 cells). Exhibits anti-proliferative activity and growth arrest in multiple cell lines (GI50 = 3.8, 0.79, and 6.3 µM in NIH 3T3, HeLa S3 and A549 cells, respectively). Shown to induce apoptotic cell death in liver cancer cell lines over-expressing LSF without affecting primary or immortalized hepatocytes. Also shown to inhibit hepatocellular carcinoma s.c. growth in mouse xenograft model without any toxic effects (1 mg/kg, i.p., once every 3 days).
    产品目录编号 438210
    品牌系列 Calbiochem®
    同义词 (±)(8-(2-Ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one, Factor Quinolinone Inhibitor 1, Racemic
    应用数据
    参考
    参考 Grant, T.J., et al. 2012. Proc. Natl. Acad. Sci. USA 109, 4503.
    产品信息
    形式 White powder
    Hill配方 C₁₈H₁₇NO₄
    化学配方 C₁₈H₁₇NO₄
    Molar Mass 311.3
    生物信息
    纯度 >92% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,438210,LSF Inhibitor, FQI1 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,05-1921,Anti-phospho IRS1 (Ser522) Antibody, clone 17.5.2
下一件merck millipore产品：merck millipore,默克密理博,376820,β-Hexosaminidase Inhibitor - CAS 281224-40-6 - Calbiochem


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