merck millipore,默克密理愽
  • merck millipore,默克密理博,376820,β-Hexosaminidase Inhibitor - CAS 281224-40-6 - Calbiochem

  • merck millipore,默克密理博,376820,β-Hexosaminidase Inhibitor - CAS 281224-40-6 - Calbiochem

    产品名称：β-Hexosaminidase Inhibitor - CAS 281224-40-6 - Calbiochem
    产品型号：376820
    The β-Hexosaminidase Inhibitor, also referenced under CAS 281224-40-6, controls the biological activity of β-Hexosaminidase. This small molecule/inhibitor is primarily used for Protease Inhibitors app More>>

    merck millipore,默克密理博,376820,β-Hexosaminidase Inhibitor - CAS 281224-40-6 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,376820,β-Hexosaminidase Inhibitor - CAS 281224-40-6 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₈H₂₁N₃O₄ • 1/2(CH₃OH)281224-40-6
    描述
    概述 A cell-permeable bisnaphthalimide compound that acts as a substrate-competitive and selective inhibitor against human β-N-acetyl hexosaminidase (IC50 = 6.0 and 3.1 µM for hHex A and hHex B, respectively), while exhibiting much reduced potency against Jack Bean or bacterial Hex (IC50 = 280 & >500 µM for JBHex & SpHex, respectively) and little or no activity against SmHex or hOGN. Shown to function as a pharmacological chaperone and effectively enhance the transport of mutant Hex alpha subunit from the ER to lysosome in cells derived from ISD and ATSD patients.
    产品目录编号 376820
    品牌系列 Calbiochem®
    同义词 M-31850
    参考
    参考 Tropak, M.B., et al. 2007. Chem. Biol. 14, 153.
    产品信息
    CAS号 281224-40-6
    形式 White solid
    Hill配方 C₂₈H₂₁N₃O₄ • 1/2(CH₃OH)
    化学配方 C₂₈H₂₁N₃O₄ • 1/2(CH₃OH)
    Molar Mass 479.5
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at 20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,376820,β-Hexosaminidase Inhibitor - CAS 281224-40-6 - Calbiochem

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