• merck millipore,默克密理博,420175,Cancer Hydrolase KIAA1363 Inhibitor, JW480 - CAS 1354359-53-7 - Calbiochem
  • merck millipore,默克密理博,420175,Cancer Hydrolase KIAA1363 Inhibitor, JW480 - CAS 1354359-53-7 - Calbiochem

    产品名称:Cancer Hydrolase KIAA1363 Inhibitor, JW480 - CAS 1354359-53-7 - Calbiochem
    产品型号:420175


    merck millipore,默克密理博,420175,Cancer Hydrolase KIAA1363 Inhibitor, JW480 - CAS 1354359-53-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,420175,Cancer Hydrolase KIAA1363 Inhibitor, JW480 - CAS 1354359-53-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₂H₂₃NO₂1354359-53-7
    描述
    概述 A membrane-permeable, highly potent and selective inhibitor against the 2-acetyl MAGE (monoakylglycerol ether) hydrolase KIAA1363/AADACL1 of both human (IC50 = 12 nM; PC3 lysate) and murine (IC50 = 20 nM; brain membrane samples) origin, with no significant effect toward other PC3 or murine brain serine hydrolase activities, including HSL, FAAH, and AChE. Readily crosses blood-brain barrier in mice and effectively suppresses PC3-derived tumor growth in mice in vivo (by 56% on day 33; 80 mg/kg/day; o.g.). Also inhibits blood carboxylesterase.
    产品目录编号 420175
    品牌系列 Calbiochem®
    同义词 2ʹ-Isopropylphenyl-2-(2-naphthyl)ethylcarbamate, AADACL1 Inhibitor, Arylacetamide Deacetylase-Like 1 Inhibitor, NCEH1 Inhibitor, Neutral Cholesterol Ester Hydrolase 1 Inhibitor
    参考
    参考 Chang, J.W., et al. 2011. Chem. Biol. 18, 476.
    产品信息
    CAS号 1354359-53-7
    形式 White powder
    Hill配方 C₂₂H₂₃NO₂
    化学配方 C₂₂H₂₃NO₂
    Molar Mass 333.4
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Regulatory Review
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,420175,Cancer Hydrolase KIAA1363 Inhibitor, JW480 - CAS 1354359-53-7 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,MAB5268,Anti-Chromogranin A Antibody, clone LK2H10
下一件merck millipore产品:merck millipore,默克密理博,AB770,Anti-TIMP-1 Antibody



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