- 当前位置:首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
- merck millipore,默克密理博,420175,Cancer Hydrolase KIAA1363 Inhibitor, JW480 - CAS 1354359-53-7 - Calbiochem
重要规格表
经验配方 CAS号 C₂₂H₂₃NO₂ 1354359-53-7 描述 概述 A membrane-permeable, highly potent and selective inhibitor against the 2-acetyl MAGE (monoakylglycerol ether) hydrolase KIAA1363/AADACL1 of both human (IC50 = 12 nM; PC3 lysate) and murine (IC50 = 20 nM; brain membrane samples) origin, with no significant effect toward other PC3 or murine brain serine hydrolase activities, including HSL, FAAH, and AChE. Readily crosses blood-brain barrier in mice and effectively suppresses PC3-derived tumor growth in mice in vivo (by 56% on day 33; 80 mg/kg/day; o.g.). Also inhibits blood carboxylesterase. 产品目录编号 420175 品牌系列 Calbiochem®
同义词 2ʹ-Isopropylphenyl-2-(2-naphthyl)ethylcarbamate, AADACL1 Inhibitor, Arylacetamide Deacetylase-Like 1 Inhibitor, NCEH1 Inhibitor, Neutral Cholesterol Ester Hydrolase 1 Inhibitor 参考 参考 Chang, J.W., et al. 2011. Chem. Biol. 18, 476. 产品信息 CAS号 1354359-53-7 形式 White powder Hill配方 C₂₂H₂₃NO₂ 化学配方 C₂₂H₂₃NO₂ Molar Mass 333.4 结构配方图像 生物信息 纯度 ≥97% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
毒性 Regulatory Review
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
上一件merck millipore产品:merck millipore,默克密理博,MAB5268,Anti-Chromogranin A Antibody, clone LK2H10
下一件merck millipore产品:merck millipore,默克密理博,AB770,Anti-TIMP-1 Antibody
merck millipore,默克密理博,SCC052,PluriStem BALB/C Murine ES Cells
merck millipore,默克密理博,05-605,Anti-Bad Antibody, clone BYC001
merck millipore,默克密理博,SF-186,HIF-1alpha; Mouse, Cyanine 5, RNA Detection Probe,SmartFlare
merck millipore,默克密理博,ABE1034,Anti-Tet1 Antibody
merck millipore,默克密理博,MAB5268,Anti-Chromogranin A Antibody, clone LK2H10
merck millipore,默克密理博,AB770,Anti-TIMP-1 Antibody
merck millipore,默克密理博,SF-500,miR-146a-5p; Human, Cyanine 5, RNA Detection Probe,SmartFlare
merck millipore,默克密理博,MABN367,Anti-SV2C Antibody, clone 4C8.1
merck millipore,默克密理博,MAB3729,Anti-c-met Antibody, clone 4AT44



