• merck millipore,默克密理博,401002,Iberiotoxin, Buthus tamulus, Recombinant, E. coli - CAS 129203-60-7 - Calbiochem
  • merck millipore,默克密理博,401002,Iberiotoxin, Buthus tamulus, Recombinant, E. coli - CAS 129203-60-7 - Calbiochem

    产品名称:Iberiotoxin, Buthus tamulus, Recombinant, E. coli - CAS 129203-60-7 - Calbiochem
    产品型号:401002
    Recombinant Buthus tamulus iberiotoxin expressed in E.

    merck millipore,默克密理博,401002,Iberiotoxin, Buthus tamulus, Recombinant, E. coli - CAS 129203-60-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,401002,Iberiotoxin, Buthus tamulus, Recombinant, E. coli - CAS 129203-60-7 - Calbiochem

    重要规格表

    CAS号
    129203-60-7
    描述
    概述 Recombinant Buthus tamulus iberiotoxin expressed in E. coli. Acts as a selective, reversible blocker of high conductance Ca2+-activated K+ channels (IC50 = 250 pM).
    产品目录编号 401002
    品牌系列 Calbiochem®
    同义词 rlbTx, Pyr-FTDVDCSVSKECWSVCKDLFGVDRGKCMGKKCRCYQ
    参考
    参考 Vanelli, G., et al. 1994. J. Appl. Physiol. 76, 1098.
    Garcia, M.L., et al. 1991. J. Bioeng. Biomembr. 23, 615.
    Galvez, A., et al. 1990. J. Biol. Chem. 265, 11083.
    产品信息
    CAS号 129203-60-7
    具有ATP竞争性 N
    形式 Salt-free lyophilized solid
    Molar Mass 4231
    肽序列 Pyr-Phe-Thr-Asp-Val-Asp-Cys⁷-Ser-Val-Ser-Lys-Glu-Cys¹³-Trp-Ser-Val-Cys¹⁷-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys²⁸-Met-Gly-Lys-Lys-Cys³³-Arg-Cys³⁵-Tyr-Gln-OH (disulfide bonds: 7 →28; 13 → 35; 17 → 33)
    可逆 Y
    生物信息
    生物活性 potently inhibits Ca2+-activated K+ channels expressed in Xenopus oocytes
    主靶 High conductance Ca2+-activated K+ channels
    主靶IC50 250 pM against high conductance Ca2+-activated K+ channels
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 100 mM NaCl, 10 mM Tris-HCl, pH 7.5 containing 0.1% BSA
    肽序列 Pyr-Phe-Thr-Asp-Val-Asp-Cys⁷-Ser-Val-Ser-Lys-Glu-Cys¹³-Trp-Ser-Val-Cys¹⁷-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys²⁸-Met-Gly-Lys-Lys-Cys³³-Arg-Cys³⁵-Tyr-Gln-OH (disulfide bonds: 7 →28; 13 → 35; 17 → 33)
    安全信息
    R相 R: 20/21/22

    Harmful by inhalation, in contact with skin and if swallowed.
    S相 S: 36

    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 -20°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 3 months at -20°C or up to 2 weeks at 4°C.

    merck millipore,默克密理博,401002,Iberiotoxin, Buthus tamulus, Recombinant, E. coli - CAS 129203-60-7 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,05-23-3831,BQ-123, Sodium Salt - CAS - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,14-742,FGFR2 (N549H) Protein, active, 10 µg



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