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merck millipore,默克密理博,401002,Iberiotoxin, Buthus tamulus, Recombinant, E. coli - CAS 129203-60-7 - Calbiochem
产品名称:Iberiotoxin, Buthus tamulus, Recombinant, E. coli - CAS 129203-60-7 - Calbiochem
产品型号:401002
Recombinant Buthus tamulus iberiotoxin expressed in E.
merck millipore,默克密理博,401002,Iberiotoxin, Buthus tamulus, Recombinant, E. coli - CAS 129203-60-7 - Calbiochem
- 产品介绍
- merck millipore,默克密理博,401002,Iberiotoxin, Buthus tamulus, Recombinant, E. coli - CAS 129203-60-7 - Calbiochem
重要规格表
CAS号 129203-60-7 描述 概述 Recombinant Buthus tamulus iberiotoxin expressed in E. coli. Acts as a selective, reversible blocker of high conductance Ca2+-activated K+ channels (IC50 = 250 pM). 产品目录编号 401002 品牌系列 Calbiochem®
同义词 rlbTx, Pyr-FTDVDCSVSKECWSVCKDLFGVDRGKCMGKKCRCYQ 参考 参考 Vanelli, G., et al. 1994. J. Appl. Physiol. 76, 1098.
Garcia, M.L., et al. 1991. J. Bioeng. Biomembr. 23, 615.
Galvez, A., et al. 1990. J. Biol. Chem. 265, 11083.产品信息 CAS号 129203-60-7 具有ATP竞争性 N 形式 Salt-free lyophilized solid Molar Mass 4231 肽序列 Pyr-Phe-Thr-Asp-Val-Asp-Cys⁷-Ser-Val-Ser-Lys-Glu-Cys¹³-Trp-Ser-Val-Cys¹⁷-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys²⁸-Met-Gly-Lys-Lys-Cys³³-Arg-Cys³⁵-Tyr-Gln-OH (disulfide bonds: 7 →28; 13 → 35; 17 → 33) 可逆 Y 生物信息 生物活性 potently inhibits Ca2+-activated K+ channels expressed in Xenopus oocytes 主靶 High conductance Ca2+-activated K+ channels 主靶IC50 250 pM against high conductance Ca2+-activated K+ channels 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 100 mM NaCl, 10 mM Tris-HCl, pH 7.5 containing 0.1% BSA 肽序列 Pyr-Phe-Thr-Asp-Val-Asp-Cys⁷-Ser-Val-Ser-Lys-Glu-Cys¹³-Trp-Ser-Val-Cys¹⁷-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys²⁸-Met-Gly-Lys-Lys-Cys³³-Arg-Cys³⁵-Tyr-Gln-OH (disulfide bonds: 7 →28; 13 → 35; 17 → 33) 安全信息 R相 R: 20/21/22
Harmful by inhalation, in contact with skin and if swallowed.S相 S: 36
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Harmful
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 3 months at -20°C or up to 2 weeks at 4°C.
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