merck millipore,默克密理愽
  • merck millipore,默克密理博,400087,HIF-2α Translation Inhibitor - CAS 882268-69-1 - Calbiochem

  • merck millipore,默克密理博,400087,HIF-2α Translation Inhibitor - CAS 882268-69-1 - Calbiochem

    产品名称：HIF-2α Translation Inhibitor - CAS 882268-69-1 - Calbiochem
    产品型号：400087
    The HIF-2α Translation Inhibitor, also referenced under CAS 882268-69-1, controls the biological activity of HIF-2α. This small molecule/inhibitor is primarily used for Cell Structure applications.

    merck millipore,默克密理博,400087,HIF-2α Translation Inhibitor - CAS 882268-69-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,400087,HIF-2α Translation Inhibitor - CAS 882268-69-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₉H₉N₃O₄S₂882268-69-1
    描述
    概述 A cell-permeable thienylhydrazone compound that suppresses the translation of cellular HIF-2α message by enhancing the binding of IRP1 (Iron-Regulatory Protein 1) to the IRE (Iron-Responsive Element) region at the 5' UTR of the HIF-2α mRNA, exhibiting otherwise no effects toward the transcription of HIF-2α mRNA or the stability of HIF-2α mRNA and protein. Shown to reduce cellular protein levels of HIF-2α and HIF-2α target genes, including Glut-1, IGFBP3, and VEGF, in 786-O cells (5 to 10 µM final concentration) that express only the 2α isoform of hypoxia-inducible factor.
    产品目录编号 400087
    品牌系列 Calbiochem®
    同义词 Hypoxia-Inducible Factor-2α Translation Inhibitor, Methyl-3-(2-(cyano(methylsulfonyl)methylene)hydrazino)thiophene-2-carboxylate, HIF Inhibitor II
    参考
    参考 Zimmer, M., et al. 2008. Mol. Cell 32, 838.
    产品信息
    CAS号 882268-69-1
    形式 Amber solid
    Hill配方 C₉H₉N₃O₄S₂
    化学配方 C₉H₉N₃O₄S₂
    Molar Mass 287.3
    结构配方图像
    生物信息
    纯度 ≥95% (sum of two isomers)
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,400087,HIF-2α Translation Inhibitor - CAS 882268-69-1 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,MABT154,Anti-Cenexin Antibody, clone 2F6.1


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