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经验配方 CAS号 CH₄N₂O₂ 127-07-1 描述 概述 Anti-neoplastic agent that blocks DNA replication by inhibiting ribonucleotide reductase. Induces apoptosis in chronic myelogenous leukemia lymphocytes. Reported to enhance the radiation effects in pancreatic adenocarcinoma cells. Releases NO in the presence of oxidizing agents. 产品目录编号 400046 品牌系列 Calbiochem®
同义词 Ribonucleotide Reductase Inhibitor I, RNR Inhibitor I 参考 参考 Leyden, D., et al. 2000. Anticancer Res. 20, 133.
Tsuchiya, K., et al. 1999. Free Radic. Biol. Med. 27, 347.
Anand, S., et al. 1995. Cancer Lett. 88, 101.产品信息 CAS号 127-07-1 具有ATP竞争性 N 形式 White solid Hill配方 CH₄N₂O₂ 化学配方 CH₄N₂O₂ Molar Mass 76.1 可逆 N 结构配方图像 生物信息 主靶 Inhibiting ribonucleotide reductase 纯度 >98% by elemental analysis 理化信息 细胞可渗透 N 溶解度 H₂O GHS安全信息 RTECS YT4900000 安全信息 R相 R: 46-61
May cause heritable genetic damage.
May cause harm to the unborn child.S相 S: 45-53
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Avoid exposure - obtain special instructions before use.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Carcinogenic / Teratogenic
储存 +2°C to +8°C
无需冷冻 No
特殊指南 Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 2 months at 4°C.
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