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描述 概述 Full length, recombinant, human histone deacetylase 6 (HDAC6) fused to GST at the N-terminus and expressed in S. frugiperda insect cells using a baculovirus expression system. Actively maintained in the cytoplasm, HDAC6 is uniquely dependent on its ubiquitin-binding domain and functions at the nexus between two cellular signaling systems, involving protein acetylation and ubiquitination. The active deacetylase is useful in the study of HDAC6 regulation and for inhibitor screening. 产品目录编号 382180 品牌系列 Calbiochem®
同义词 HDAC6, Human, Recombinant 参考 参考 Pandey, U.B., et al. 2007. Nature 447, 859.
Hubbert, C., et al. 2002. Nature 417, 455.产品信息 形式 Liquid 配方 In 138 mM NaCl, 25 mM Tris-HCl, 0.05% Tween®-20 detergent, 10% glycerol, pH 8.0. Molar Mass 59000 生物信息 纯度 ≥80% by SDS-PAGE 特异活性 ≥50 units/µg protein 浓缩标签 Please refer to vial label for lot-specific concentration
储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C).
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