merck millipore,默克密理博,376817,Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3

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merck millipore,默克密理博,376817,Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3 - Calbiochem
产品名称：Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3 - Calbiochem
产品型号：376817
The Hexokinase II Inhibitor II, 3-BP, also referenced under CAS 1113-59-3, controls the biological activity of Hexokinase II. This small molecule/inhibitor is primarily used for Cell Structure applica More>>

merck millipore,默克密理博,376817,Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3 - Calbiochem

产品介绍

merck millipore,默克密理博,376817,Hexokinase II Inhibitor II, 3-BP - CAS 1113-59-3 - Calbiochem

重要规格表

经验配方	CAS号
C₃H₃BrO₃	1113-59-3

描述
概述	A cell-permeable pyruvic acid derivative that acts as an inhibitor against hexokinase II-mediated glycolysis and effectively suppress tumor survival both in cultures in vitro and in mice and rats in vivo.
产品目录编号	376817
品牌系列	Calbiochem®
同义词	3-BrPA, Bromopyruvate, Bromopyruvatic Acid, 3-Bromo-2-oxopropionic acid

参考
参考	Bujis, M., et al. 2009. Invest. New Drugs 27, 120. Chen, Z., et al. 2009. Biochim. Biophys. Acta. 1787, 553. Hulleman, E., et al. 2009. Blood. 113, 2014; Mathupala, S.P., et al. 2009. Semin. Cancer Biol. 19, 17. Pereira da Silva, A.P., et al. 2009. Biochem. J. 417, 717. Yun, J., et al. 2009. Science. 325, 1555. Zhang, X., et al. 2009. Anticancer Res. 29, 1443. Kim, J.S., et al. 2008. J. Bioenerg. Biomembr. 40, 607.

参考

Bujis, M., et al. 2009. Invest. New Drugs 27, 120.
Chen, Z., et al. 2009. Biochim. Biophys. Acta. 1787, 553.
Hulleman, E., et al. 2009. Blood. 113, 2014;
Mathupala, S.P., et al. 2009. Semin. Cancer Biol. 19, 17.
Pereira da Silva, A.P., et al. 2009. Biochem. J. 417, 717.
Yun, J., et al. 2009. Science. 325, 1555.
Zhang, X., et al. 2009. Anticancer Res. 29, 1443.
Kim, J.S., et al. 2008. J. Bioenerg. Biomembr. 40, 607.

产品信息
CAS号	1113-59-3
EC号	214-206-5
形式	White crystalline solid
Hill配方	C₃H₃BrO₃
化学配方	C₃H₃BrO₃
Molar Mass	166.96
结构配方图像

生物信息
纯度	≥97% by Titration

理化信息
溶解度	DMSO or dH₂O

GHS安全信息
RTECS	UZ0840000

安全信息
R相	R: 34 Causes burns.
S相	S: 26-36/37/39-45 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

储存和货运信息
货运代码	Blue Ice Only
毒性	Corrosive
有害材料注意事项：	Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存	+2°C to +8°C
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.