merck millipore,默克密理愽
  • merck millipore,默克密理博,371724,GPR119 Agonist, AS1269574 - CAS 330981-72-1 - Calbiochem

  • merck millipore,默克密理博,371724,GPR119 Agonist, AS1269574 - CAS 330981-72-1 - Calbiochem

    产品名称：GPR119 Agonist, AS1269574 - CAS 330981-72-1 - Calbiochem
    产品型号：371724
    The GPR119 Agonist, AS1269574, also referenced under CAS 330981-72-1, controls the biological activity of GPR119. This small molecule/inhibitor is primarily used for Biochemicals applications.

    merck millipore,默克密理博,371724,GPR119 Agonist, AS1269574 - CAS 330981-72-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,371724,GPR119 Agonist, AS1269574 - CAS 330981-72-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₃H₁₄BrN₃O330981-72-1
    描述
    概述 A pyrimidine compound that acts as an effective GPR119 agonist (EC50 = 2.5 µM in stimulating cAMP in hGPR119-expressing HEK293 cells) and reportedly exhibits no activity toward β-adrenergic or GLP-1 receptors. Shown to enhance 16.8 mM glucose-induced insulin secretion from murine MIN-6 β-cells (mU/20 min = 0.44 and 0.22, respectively, with or without 10 µM AS1269574) in vitro and improve glucose tolerance in normal mice (100 mg/kg; p.o.) without any significant hypoglycemic effect in vivo.
    产品目录编号 371724
    品牌系列 Calbiochem®
    同义词 2-((2-(4-Bromophenyl)-6-methylpyrimidin-4-yl)amino)ethanol, G-Protein Coupled Receptor 119 Agonist, GPCR2 Agonist, MGC119957 Agonist, SNORF25 Agonist
    参考
    参考 Yoshida, S., et cl. 2010. Biochem. Biophys. Res. Commun. 400, 437.
    产品信息
    CAS号 330981-72-1
    形式 Amber solid
    Hill配方 C₁₃H₁₄BrN₃O
    化学配方 C₁₃H₁₄BrN₃O
    Molar Mass 308.2
    结构配方图像
    生物信息
    纯度 ≥99% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Regulatory Review
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,371724,GPR119 Agonist, AS1269574 - CAS 330981-72-1 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,70599,pETBlue-1 AccepTor™ Vector (linearized vector) - Novagen
下一件merck millipore产品：merck millipore,默克密理博,9310-OP,OmniPur TRIS Hydrochloride - CAS 1185-53-1 - Calbiochem


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