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merck millipore,默克密理博,370655,PKG Iα Inhibitor, Cell-Permeable - Calbiochem
产品名称:PKG Iα Inhibitor, Cell-Permeable - Calbiochem
产品型号:370655
The PKG Iα Inhibitor, Cell-Permeable controls the biological activity of PKG Iα. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
merck millipore,默克密理博,370655,PKG Iα Inhibitor, Cell-Permeable - Calbiochem
- 产品介绍
重要规格表
经验配方 C₁₅₂H₂₅₈N₅₂O₂₈S 描述 概述 A highly potent, reversible, and substrate competitive membrane-permeable Drosophila Antennapedia homeodomain fused-peptide that selectively inhibits protein kinase G Iα (Ki = 25 nM). Shown to efficiently translocate into arterial smooth muscle cells and inhibit NO-induced vasodilation (ED50 = 47 µM). Inhibits protein kinase A at much higher concentrations (Ki = 493 µM). The carrier peptide is also available under Cat. no. 287895. 产品目录编号 370655 品牌系列 Calbiochem®
同义词 DT-3, RQIKIWFQNRRMKWKKLRKKKKKH, PKG Inhibitor VIII 参考 参考 Dostmann, W. R.G., et al. 2000. Proc. Natl. Acad. Sci. USA 97, 14772. 产品信息 具有ATP竞争性 Y 形式 Lyophilized 配方 Supplied as a trifluoroacetate salt. Hill配方 C₁₅₂H₂₅₈N₅₂O₂₈S 化学配方 C₁₅₂H₂₅₈N₅₂O₂₈S Molar Mass 3294.1 吸湿 Hygroscopic
肽序列 H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Leu-Arg-Lys-Lys-Lys-Lys-Lys-His-OH 可逆 Y 生物信息 主靶 PKG1α 主靶Ki 25 nM against protein kinase G Iα 纯度 ≥95% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO 肽序列 H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Leu-Arg-Lys-Lys-Lys-Lys-Lys-His-OH 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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