merck millipore,默克密理愽
  • merck millipore,默克密理博,368044,Granzyme A, Human, Recombinant, E. coli

  • merck millipore,默克密理博,368044,Granzyme A, Human, Recombinant, E. coli

    产品名称：Granzyme A, Human, Recombinant, E. coli
    产品型号：368044


    merck millipore,默克密理博,368044,Granzyme A, Human, Recombinant, E. coli

  • 产品介绍
  • merck millipore,默克密理博,368044,Granzyme A, Human, Recombinant, E. coli

    重要规格表
    描述
    概述 Recombinant, human granzyme A expressed in E. coli. Granzyme A is a trypsin-like serine protease secreted by cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. A proapoptotic enzyme that induces cell death through caspase-independent mechanism, causing single-stranded DNA nicking and other apoptotic features including nuclear fragmentation, chromatin condensation, loss of mitochondrial potential, and membrane blebbing. Granzyme A is also known to bind to and cleave nucleolin and activate the thrombin receptor on neuronal cells and astrocytes. It also cleaves and activates interleukin-1β. Note: The M.W. is that of a homodimer.
    产品目录编号 368044
    品牌系列 Calbiochem®
    同义词 GzmA
    参考
    参考 Fan, Z., et al. 2002. Mol. Cell. Biol. 22, 2810.
    Russell, J.H., and Ley, T. J. 2002. Annu. Rev. Immunol. 20, 323.
    Beresford, P.J., et al. 2001. J. Biol. Chem. 276, 43285.
    Simon, M.M., and Kramer, M.D. 1994. Methods Enzymol. 244, 68.
    产品信息
    EC号 3.4.21.78
    形式 Liquid
    配方 In 520 mM NaCl, 50 mM MES, 10% glycerol, pH 6.0.
    Molar Mass 51632
    生物信息
    特异活性 ≥100 units/µg protein
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Standard Handling
    储存 ≤ -70°C
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-70°C).

    merck millipore,默克密理博,368044,Granzyme A, Human, Recombinant, E. coli

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