• merck millipore,默克密理博,361515,Glycogen Phosphorylase Inhibitor - CAS 648926-15-2 - Calbiochem
  • merck millipore,默克密理博,361515,Glycogen Phosphorylase Inhibitor - CAS 648926-15-2 - Calbiochem

    产品名称:Glycogen Phosphorylase Inhibitor - CAS 648926-15-2 - Calbiochem
    产品型号:361515
    The Glycogen Phosphorylase Inhibitor, also referenced under CAS 648926-15-2, controls the biological activity of Glycogen Phosphorylase.

    merck millipore,默克密理博,361515,Glycogen Phosphorylase Inhibitor - CAS 648926-15-2 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,361515,Glycogen Phosphorylase Inhibitor - CAS 648926-15-2 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₇H₁₅ClF₂N₄O₄648926-15-2
    描述
    概述 A cell-permeable urea compound that acts as a potent and AMP-competitive inhibitor of glycogen phosphorylase (GP; IC50 = 53 nM). Shown to inhibit glucagon-induced glyocgenolysis both in hepatocytes (IC50 = 380 nM) in vitro and in rats (5 mg/kg, iv) in vivo.
    产品目录编号 361515
    品牌系列 Calbiochem®
    同义词 1-(3-(3-(2-Chloro-4,5-difluorobenzoyl)ureido)-4-methoxyphenyl)-3-methylurea
    参考
    参考 Klabunde, T., et al. 2005. J. Med. Chem. 48, 6178
    产品信息
    CAS号 648926-15-2
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₁₇H₁₅ClF₂N₄O₄
    化学配方 C₁₇H₁₅ClF₂N₄O₄
    Molar Mass 412.8
    可逆 N
    结构配方图像
    生物信息
    主靶 Glycogen phosphorylase
    主靶IC50 53 nM against glycogen phosphorylase
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,361515,Glycogen Phosphorylase Inhibitor - CAS 648926-15-2 - Calbiochem

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