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描述 概述 Recombinant, human galectin-3 expressed in E. coli and subsequently cleaved with Clostridium histolyticum collagenase type VII to yield galectin-3C. The resulting galectin-3C is purified by affinity chromatography. Galectin-3C is a truncated form of galectin-3 that contains the carbohydrate binding domain but lacks the 107 amino acids at the N-terminus of galectin-3. It is suggested to play a key role in autoimmune diseases, allergic reactions, inflammation, tumor cell metastasis, atherosclerosis, and diabetes. 产品目录编号 345832 品牌系列 Calbiochem®
参考 参考 Hoyer K.K., et al. 2004. Am. J. Pathol. 164, 893.
John C.M., et al. 2003. Clin. Cancer Res. 9, 2374.
Iurisci, I., et al. 2000. Clin Cancer Res 6, 1389.
Van Den Brule, F. A., et al. 2000. Int. J. Cancer 89, 361.
Inohara, H. 1999. Cancer 85, 2475.
Nakamura, M., et al. 1999. Int. J. Oncol. 15, 143.
Idikio, H., et al. 1998. Int. J. Oncol. 12, 1287.
Ochieng, J., et al. 1998. Biochim. Biophys. Acta. 1379 97.
Castronovo, V., et al. 1996. J. Pathol. 179, 43.
Liu, F.T., et al. 1996. Biochemistry 35 6073.
Schoeppner, H. L., et al. 1995. Cancer 75, 2818.
Massa, S.M., et al. 1993. Biochemistry 32, 260.
Oda, Y., et al. 1991. Gene 99, 279.产品信息 形式 Lyophilized 配方 Lyophilized from deionized water, 2µg lactose/µg lectin. Molar Mass 16000 生物信息 纯度 ≥95% by SDS-PAGE 理化信息 污染物 Endotoxin: ≤ 1 EU/µg protein 溶解度 Sterile PBS 储存和货运信息 货运代码 Blue Ice Only
毒性 Standard Handling
储存 -20°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions (in the presence of a molar excess of lactose) are stable for up to 4 months at -20°C. For use in carbohydrate binding assays the solution should be dialyzed to remove the lactose stabilizer.
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