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merck millipore,默克密理博,344931,Furin Inhibitor II - Calbiochem
产品名称：Furin Inhibitor II - Calbiochem
产品型号：344931
The Furin Inhibitor II controls the biological activity of Furin. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
merck millipore,默克密理博,344931,Furin Inhibitor II - Calbiochem
- 产品介绍
重要规格表
经验配方 C₃₆H₇₅N₂₅O₆ 描述 概述 A polyarginine compound that acts as a potent, specific, and competitive inhibitor of furin (Ki = 106 nM). Inhibits Subtilisin-like proprotein convertase 4 (PACE4) and prohormone convertase 1 (PC1) at much higher concentration (Ki = 580 nM and 13 µM, respectively). Has a stimulatory effect on the activity of prohormone convertase 2 (PC2). The D-peptides are suggested to be more resistant to in vivo hydrolysis than L-peptides. 产品目录编号 344931 品牌系列 Calbiochem®
同义词 Hexa-D-arginine, H-(D)RRRRRR-NH₂ 参考 参考 Cameron, A., et al. 2000. J. Biol. Chem. 275, 36741. 产品信息 具有ATP竞争性 Y 形式 White solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₃₆H₇₅N₂₅O₆ 化学配方 C₃₆H₇₅N₂₅O₆ Molar Mass 954.2 吸湿 Hygroscopic
肽序列 H-(D)Arg-Arg-Arg-Arg-Arg-Arg-NH₂ 可逆 N 生物信息 主靶 furin 主靶Ki 106 nM against Furin 纯度 ≥95% by HPLC 理化信息 细胞可渗透 N 溶解度 H₂O 肽序列 H-(D)Arg-Arg-Arg-Arg-Arg-Arg-NH₂ 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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