merck millipore,默克密理愽
  • merck millipore,默克密理博,343020,Flt-3 Inhibitor - CAS 301305-73-7 - Calbiochem

  • merck millipore,默克密理博,343020,Flt-3 Inhibitor - CAS 301305-73-7 - Calbiochem

    产品名称：Flt-3 Inhibitor - CAS 301305-73-7 - Calbiochem
    产品型号：343020
    The Flt-3 Inhibitor, also referenced under CAS 301305-73-7, controls the biological activity of Flt-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicati More>>

    merck millipore,默克密理博,343020,Flt-3 Inhibitor - CAS 301305-73-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,343020,Flt-3 Inhibitor - CAS 301305-73-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₈H₂₀N₂O₄S301305-73-7
    描述
    概述 A cell-permeable thienylcarboxamide compound that acts as a potent, ATP-competitive, and highly selective Flt-3 inhibitor (IC50 = 42 nM) with little effect against a panel of 22 other kinases (IC50 ≥3 µM). Shown to exhibit antiproliferative properties against the human acute myelogenous leukemia cell line MV4-11 (IC50 = 340 nM) expressing constitutively active Flt-3.
    产品目录编号 343020
    品牌系列 Calbiochem®
    参考
    参考 Patch, R.J., et al. 2006. Bioorg. Med. Chem. Lett. 16, 3282.
    产品信息
    CAS号 301305-73-7
    具有ATP竞争性 Y
    形式 White solid
    Hill配方 C₁₈H₂₀N₂O₄S
    化学配方 C₁₈H₂₀N₂O₄S
    Molar Mass 360.4
    可逆 N
    结构配方图像
    生物信息
    主靶 Flt-3
    主靶IC50 42 nM against Flt-3
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,343020,Flt-3 Inhibitor - CAS 301305-73-7 - Calbiochem

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