merck millipore,默克密理愽
  • merck millipore,默克密理博,33-039,PI 3-Kinase Class II HTRF Assay

  • merck millipore,默克密理博,33-039,PI 3-Kinase Class II HTRF Assay

    产品名称：PI 3-Kinase Class II HTRF Assay
    产品型号：33-039
    Five-plate kit (1920 wells) of reagents for performing PI 3-Kinase (Class II) 4-step HTRF assays. Suitable for the following Kinases: PI3KC2α, PI3KC2β & PI3KC2γ.

    merck millipore,默克密理博,33-039,PI 3-Kinase Class II HTRF Assay

  • 产品介绍
  • merck millipore,默克密理博,33-039,PI 3-Kinase Class II HTRF Assay

    描述
    产品目录编号 33-039
    品牌系列 Upstate
    商名
    • Upstate
    • HTRF
    描述 PI 3-Kinase Class II HTRF Assay
    产品信息
    部件
    • Stop Reagent C
    • Reaction Buffer (4X)
    • DM A Detection Reagent
    • DM C Detection Reagent
    • DM D Detection Reagent
    • Phosphatidylinositol (1mM)
    • Phosphatidylserine (1mM)
    检测方法 HTRF
    应用
    应用 Five-plate kit (1920 wells) of reagents for performing PI 3-Kinase (Class II) 4-step HTRF assays. Suitable for the following Kinases: PI3KC2α, PI3KC2β & PI3KC2γ.
    主要应用
    • Kinase Assay
    生物信息
    品种反应性 MouseHuman
    可用的分析物
    • PI 3-Kinase Class II
    Entrez基因编号
    • NM_004570.4
    • NM_002645.2
    • NM_002646.3
    Entrez基因汇总 Phosphoinositide 3-kinase-C2 proteins generate phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers. This protein belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner.
    基因符号
    • PI3KC2γ
    • PI3KC2α
    • PI3KC2β
    靶子系列 PI3K/PI4K
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 12 months at -70°C
    包装信息
    数量 1920 wells
    包装 Kit capacity: 1920 wells

    merck millipore,默克密理博,33-039,PI 3-Kinase Class II HTRF Assay

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