merck millipore,默克密理愽
  • merck millipore,默克密理博,328500,ERO1 Inhibitor I, Erodoxin - Calbiochem

  • merck millipore,默克密理博,328500,ERO1 Inhibitor I, Erodoxin - Calbiochem

    产品名称：ERO1 Inhibitor I, Erodoxin - Calbiochem
    产品型号：328500
    The ERO1 Inhibitor I, Erodoxin controls the biological activity of ERO1.

    merck millipore,默克密理博,328500,ERO1 Inhibitor I, Erodoxin - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,328500,ERO1 Inhibitor I, Erodoxin - Calbiochem

    重要规格表

    经验配方
    C₇H₅BrN₂O₅
    描述
    概述 A cell-permeable dinitrobromobenzene compound that acts as a selective inhibitor of yeast Endoplasmic Reticulum Oxidase 1 (ERO1), but has somewhat weaker activity against mouse ERO1α (IC50 = 400 µM). Predicted to form thiol adducts and inhibits ERO1-dependent oxidation of thioredoxin-1 (Trx1) activity in vitro. Shown to cluster with genes involved in protein folding, glycosylation and cell wall biosynthesis, and delay carboxypeptidase Y (CPY) processing to the vacuolar form in wt-yeast cells.
    产品目录编号 328500
    品牌系列 Calbiochem®
    同义词 1-Bromo-5-methoxy-2,4-dinitrobenzene, Endoplasmic Reticulum Oxidase 1 Inhibitor
    参考
    参考 Costanzo, M., et al. 2010. Science 327, 425.
    Blais, J.D., et al. 2010. J. Biol. Chem. 285, 20993.
    产品信息
    形式 Yellow solid
    Hill配方 C₇H₅BrN₂O₅
    化学配方 C₇H₅BrN₂O₅
    Molar Mass 277.0
    结构配方图像
    生物信息
    纯度 ≥99% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze(-20°C). Stock solutions are stable for up to 1 month at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,328500,ERO1 Inhibitor I, Erodoxin - Calbiochem

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