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merck millipore,默克密理博,324813,Soluble Epoxide Hydrolase Inhibitor, NCND - CAS 402939-18-8 - Calbiochem
产品名称：Soluble Epoxide Hydrolase Inhibitor, NCND - CAS 402939-18-8 - Calbiochem
产品型号：324813
The Soluble Epoxide Hydrolase Inhibitor, NCND, also referenced under CAS 402939-18-8, controls the biological activity of Soluble Epoxide Hydrolase.
merck millipore,默克密理博,324813,Soluble Epoxide Hydrolase Inhibitor, NCND - CAS 402939-18-8 - Calbiochem
- 产品介绍
- merck millipore,默克密理博,324813,Soluble Epoxide Hydrolase Inhibitor, NCND - CAS 402939-18-8 - Calbiochem
描述 概述 A cell-permeable 1,3-disubstituted urea compound that displays anti-hypertensive and anti-inflammatory properties. Acts as a potent, selective, competitive, and tight-binding transition-state analog inhibitor of soluble epoxide hydrolase (sEH; IC50 = 9.8 nM for mouse recombinant sEH, 85.2 nM for human recombinant sEH). Reported to decrease human VSMC (vascular smooth muscle cell) proliferation. 产品目录编号 324813 品牌系列 Calbiochem®
同义词 CDU, N-Cyclohexyl-Nʹ-dodecylurea, 1-Cyclohexyl-3ʹ-dodecylurea 参考 参考 Newman, J.W., et al. 2003. Proc. Natl. Acad. Sci. USA 100, 1558.
Davis, B.B., et al. 2002. Proc. Natl. Acad. Sci. USA 99, 2222.
Morisseau, C., et al. 2002. Biochem. Pharmacol. 63, 1599.
Imig, J.D., et al. 2002. Hypertension 39, 690.
Argiriadi, M.A., et al. 2000. J. Biol. Chem. 275, 15265.
Yu, Z., et al. 2000. Circ. Res. 87, 992.
产品信息 CAS号 402939-18-8 具有ATP竞争性 Y 形式 White solid Hill配方 C₁₉H₃₈N₂O 化学配方 C₁₉H₃₈N₂O Molar Mass 310.5 可逆 N 结构配方图像 生物信息 主靶 Soluble epoxide hydrolase 主靶IC50 9.8 nM for mouse recombinant sEH, 85.2 nM for human recombinant sEH 纯度 ≥95% by TLC 理化信息 细胞可渗透 Y 溶解度 CH₂Cl₂ 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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