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merck millipore,默克密理博,324517,eIF4E/eIF4G Interaction Inhibitor, 4EGI-1 - CAS 315706-13-9 - Calbiochem
产品名称：eIF4E/eIF4G Interaction Inhibitor, 4EGI-1 - CAS 315706-13-9 - Calbiochem
产品型号：324517
The eIF4E/eIF4G Interaction Inhibitor, 4EGI-1, also referenced under CAS 315706-13-9, controls the biological activity of eIF4E/eIF4G interaction. This small molecule/inhibitor is primarily used for P More>>
merck millipore,默克密理博,324517,eIF4E/eIF4G Interaction Inhibitor, 4EGI-1 - CAS 315706-13-9 - Calbiochem
- 产品介绍
- merck millipore,默克密理博,324517,eIF4E/eIF4G Interaction Inhibitor, 4EGI-1 - CAS 315706-13-9 - Calbiochem
重要规格表
经验配方 CAS号 C₁₈H₁₂Cl₂N₄O₄S 315706-13-9 描述 概述 A cell-permeable hydrazone compound that reversibly binds eukaryotic translation initiation factor 4E (eIF4E; KD = 25 µM) and disrupts eIF4E/eIF4G, but not eIF4E/4E-BP1, complex formation. Reported to downregulate the protein, but not mRNA, levels of c-Myc and Bcl-xL in Jurkat cells (8 h), leading to apoptotic cell death after prolonged exposure (24 h, IC50 = ~ 25 µM). Also available as a 25 mM solution in DMSO (Cat. No. 324519). 产品目录编号 324517 品牌系列 Calbiochem®
同义词 2-((4-(3,4-Dichlorophenyl)-thiazol-2-ylhydrazono)-3-(2-nitrophenyl))propionic acid, eIF4F Inhibitor I 参考 参考 Moerke, N. J., et al. 2007. Cell 128, 257. 产品信息 CAS号 315706-13-9 形式 Yellow solid Hill配方 C₁₈H₁₂Cl₂N₄O₄S 化学配方 C₁₈H₁₂Cl₂N₄O₄S Molar Mass 451.3 结构配方图像 生物信息 纯度 ≥98% by HPLC (sum of two isomers) 理化信息 溶解度 DMSO 安全信息 R相 R: 22
Harmful if swallowed.S相 S: 36-45
Wear suitable protective clothing.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).储存和货运信息 货运代码 Ambient Temperature Only
毒性 Harmful
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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