• merck millipore,默克密理博,287815,3,4-Dichloroisocoumarin - CAS 51050-59-0 - Calbiochem
  • merck millipore,默克密理博,287815,3,4-Dichloroisocoumarin - CAS 51050-59-0 - Calbiochem

    产品名称:3,4-Dichloroisocoumarin - CAS 51050-59-0 - Calbiochem
    产品型号:287815


    merck millipore,默克密理博,287815,3,4-Dichloroisocoumarin - CAS 51050-59-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,287815,3,4-Dichloroisocoumarin - CAS 51050-59-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₉H₄Cl₂O₂51050-59-0
    描述
    概述 A potent, irreversible inhibitor of serine proteases. Reacts with serine proteases to release an acylchloride moiety that can acylate another active site residue. Inhibits granzyme B and blocks apoptotic internucleosomal DNA cleavage in thymocytes without the involvement of endonucleases. Does not affect thiol proteases and metalloproteases. Does not exhibit any activity towards β-lactamases.
    Effective concentration: 5-100 µM; t½ = 20 min at pH 7.5.
    产品目录编号 287815
    品牌系列 Calbiochem®
    参考
    参考 Cain, K., et al. 1994. Biochem. Cell Biol. 72, 631.
    Weaver, V.M., et al. 1993. Biochem. Cell Biol. 71, 488.
    Odake, S., et al. 1991. Biochemistry 30, 2217.
    Harper, J.W., et al. 1985. Biochemistry 24, 1831.
    产品信息
    CAS号 51050-59-0
    具有ATP竞争性 N
    形式 White lyophilized solid
    Hill配方 C₉H₄Cl₂O₂
    化学配方 C₉H₄Cl₂O₂
    Molar Mass 215.0
    可逆 N
    结构配方图像
    生物信息
    主靶 serine proteases
    主靶IC50 5-100 µM
    纯度 ≥99% by elemental analysis
    理化信息
    细胞可渗透 N
    溶解度 DMF or DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    防潮 Protect from moisture
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

    merck millipore,默克密理博,287815,3,4-Dichloroisocoumarin - CAS 51050-59-0 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,12-344,Acetyl-Histone H4 (Lys8) Peptide
下一件merck millipore产品:merck millipore,默克密理博,128125,Aloisine A - CAS 496864-16-5 - Calbiochem



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