merck millipore,默克密理愽
  • merck millipore,默克密理博,236011,COX-2 Inhibitor I - CAS 416901-58-1 - Calbiochem

  • merck millipore,默克密理博,236011,COX-2 Inhibitor I - CAS 416901-58-1 - Calbiochem

    产品名称：COX-2 Inhibitor I - CAS 416901-58-1 - Calbiochem
    产品型号：236011
    The COX-2 Inhibitor I, also referenced under CAS 416901-58-1, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications.

    merck millipore,默克密理博,236011,COX-2 Inhibitor I - CAS 416901-58-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,236011,COX-2 Inhibitor I - CAS 416901-58-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₈H₁₆ClNO₄S416901-58-1
    描述
    概述 A cell-permeable potent and selective inhibitor of COX-2 from human monocytes (IC50 = 650 nM) and in whole blood (IC50 = 4.3 µM). Displays only very weak activity against COX-1 from human platelets (IC50 > 10 µM) and in whole blood (IC50 > 100 µM).
    产品目录编号 236011
    品牌系列 Calbiochem®
    同义词 LM-1685, Methyl [5-methylsulfonyl-1-(4-chlorobenzyl)-1H-2-indolyl]carboxylate
    参考
    参考 Palomer, A., et al. 2002. J. Med. Chem. 45, 1402.
    产品信息
    CAS号 416901-58-1
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₁₈H₁₆ClNO₄S
    化学配方 C₁₈H₁₆ClNO₄S
    Molar Mass 377.8
    可逆 N
    结构配方图像
    生物信息
    主靶 COX-2 from human monocytes
    主靶IC50 650 nM against COX-2 from human monocytes; 4.3 µM against COX-2 in whole blood
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or MeOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,236011,COX-2 Inhibitor I - CAS 416901-58-1 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,04-337,Anti-EGFR Antibody, clone E114, rabbit monoclonal
下一件merck millipore产品：merck millipore,默克密理博,440203,LY 303511 - CAS 154447-38-8 - Calbiochem


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