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经验配方 CAS号 C₂₁H₂₅NO₅ 477-30-5 描述 概述 Cell synchronization agent. Induces apoptosis by blocking mitosis in HeLa S3 cells. Depolymerizes microtubules and limits microtubule formation. Appropriate dilutions inactivate spindle fiber mechanism during metaphase, systematically immobilizing chromosomes at the metaphase plate. 产品目录编号 234109 品牌系列 Calbiochem®
同义词 Demecolcine 参考 参考 Urbani, L., et al. 1995. Exp. Cell Res. 219, 159.
Kanda, R., et al. 1994. J. Radiat. Res. 35, 41.
Sherwood, S.W., et al. 1994. Exp. Cell Res. 215, 373.
Nishiyama, I., and Fuji, T. 1992. Exp. Cell Res. 198, 214.
Spoerri, P.E., and Roisen, F.J. 1992. J. Neurosci. Res. 31, 494.产品信息 CAS号 477-30-5 具有ATP竞争性 N 形式 Crystalline powder Hill配方 C₂₁H₂₅NO₅ 化学配方 C₂₁H₂₅NO₅ Molar Mass 371.4 可逆 N 结构配方图像 生物信息 主靶 Depolymerizes microtubules and limits microtubule formation. 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 EtOH GHS安全信息 RTECS GH0800000 安全信息 R相 R: 25-63
Toxic if swallowed.
Possible risk of harm to the unborn child.S相 S: 22-36/37/39-45
Do not breathe dust.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).储存和货运信息 货运代码 Ambient Temperature Only
毒性 Toxic & Carcinogenic / Teratogenic
有害材料注意事项: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存 +15°C to +30°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C) under an inert gas. Stock solutions are stable for up to 6 months at -20°C.
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