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描述 概述 Native coagulation factor XIII from human plasma. Plasma Factor XIII is a tetramer (α2β2) composed of two identical α-subunits and two identical β-subunits. After thrombin cleavage converts the α2β2 tetramer to a modified α2′β2 tetramer, Ca2+ promotes both the dissociation of the β2 dimer and the activation of the α2′ dimer to its catalytically active form. This activated Factor XIII (Factor XIIIa) strengthens the fibrin clot by catalyzing the formation of glutamyl-lysine bonds between fibrin monomers. 产品目录编号 233501 品牌系列 Calbiochem®
同义词 Fibrin-stabilizing Factor 产品信息 CAS号 9013-56-3 形式 Liquid 配方 In 500 µM EDTA, 50% glycerol. Molar Mass 340000 生物信息 纯度 ≥95% by SDS-PAGE 来源 Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. 特异活性 ≥40 units/mg protein (clotting assay) 浓缩标签 Please refer to vial label for lot-specific concentration
储存和货运信息 货运代码 Blue Ice Only
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-20°C).
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