merck millipore,默克密理愽
  • merck millipore,默克密理博,23-057,Smac/DIABLO

  • merck millipore,默克密理博,23-057,Smac/DIABLO

    产品名称：Smac/DIABLO
    产品型号：23-057


    merck millipore,默克密理博,23-057,Smac/DIABLO

  • 产品介绍
  • merck millipore,默克密理博,23-057,Smac/DIABLO

    描述
    产品目录编号 23-057
    品牌系列 Upstate
    商名
    • Upstate
    描述 Smac/DIABLO
    长描述 C-terminal cMyc and 6His-tagged, recombinant human Smac/DIABLO amino acids 56-end, expressed in E.coli
    Alternate Names
    • Second mitochondria-derived activator of caspase (Smac)
    • Diablo homolog, mitochondrial
    • Direct IAP-binding protein with low pI
    背景信息 Smac/DIABLO is a mitochondrial protein that is proteolytically processed and released during apoptosis along with cytochrome c and other pro-apoptotic factors. Once in the cytosol, Smac/DIABLO binds to inhibitors of apoptosis (IAP) proteins and disrupts the ability of the IAPs to inhibit caspases 3, 7, and 9 thereby promoting apoptosis. Along with several other pro-apoptotic proteins, Smac/DIABLO has been shown to be a substrate for the ubiquitin ligase XIAP.
    应用
    主要应用
    • Enzyme Assay
    生物信息
    品种 Human
    级联部件 Substrate
    Entrez基因编号
    • NM_019887
    纯化方法 Purified using immobilized metal affinity chromatography
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    包装信息
    数量 10 µg

    merck millipore,默克密理博,23-057,Smac/DIABLO

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