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经验配方 C₂₈H₂₉N₃O₅ 描述 概述 An epoxysuccinyl peptide highly selective for rat liver cathepsin L (IC50 = 1.9 nM), while exhibiting little to no effect on rat liver cathepsin B at concentrations higher than 1000-5000 nM, in vitro. During autophagy, it has been shown through immunoblotting that CAA0225 (10 µg/ml) effectively inhibits the degradation of LC3-II and GABARAP compared to control, in nutrient-deprived HeLa and Huh-7 cells. 产品目录编号 219502 品牌系列 Calbiochem®
参考 参考 Takahashi, K., et al. 2009. Biol. Pharm. Bull. 32, 475.
Ueno, T., et al. 2009. Autophagy 5, 878.产品信息 形式 White solid Hill配方 C₂₈H₂₉N₃O₅ 化学配方 C₂₈H₂₉N₃O₅ Molar Mass 487.55 结构配方图像 生物信息 纯度 ≥ 95% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Shipped with Blue Ice or with Dry Ice
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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