merck millipore,默克密理愽
  • merck millipore,默克密理博,09-162,Anti-Wnt3A Antibody

  • merck millipore,默克密理博,09-162,Anti-Wnt3A Antibody

    产品名称：Anti-Wnt3A Antibody
    产品型号：09-162
    Anti-Wnt3A Antibody is an antibody against Wnt3A for use in WB, IH(P).

    merck millipore,默克密理博,09-162,Anti-Wnt3A Antibody

  • 产品介绍
  • merck millipore,默克密理博,09-162,Anti-Wnt3A Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 09-162
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-Wnt3A Antibody
    背景信息 The Wnt family of consists of ligands involved in cell development, fate determination, organogenesis, and oncogenesis. Information on Wnt signaling has been inferred from genetic analysis of wingless (wg) signaling in Drosophila. The Wnt signaling cascade initiates at the cell membrane when Wnt interacts with its receptor, a member of the Frizzled (Fz) transmembrane receptor family and lipoprotein receptor–related proteins 5 and 6 (LRP-5/6). This interaction relays the signal into the interior of the cell where disheveled (dsh) is brought to the membrane and gets phosphorylated/activated. Dsh promotes the inactivation of GSK3 kinase activity, thus preventing the phosphorylation of β-Catenin and allowing it to accumulate as it avoids ubiquination and subsequent proteosome degradation. Stable β-Catenin accumulates in the cytoplasm where it interacts with lymphoid enhancer factor/T cell factor (LEF/TCF) and translocates into the nucleus. This results in activation of TCF-responsive genes which are thought to play key roles in development and cancer. Negative regulators of the pathway may include axin and the tumor suppressor APC.
    产品信息
    格式 Affinity Purified
    演示 Affinity purified rabbit polyclonal in storage buffer containing PBS and 0.05% sodium azide.
    应用
    应用 Anti-Wnt3A Antibody is an antibody against Wnt3A for use in WB, IH(P).
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 Synthetic KLH-conjugated peptide directed against the central region of human, mouse, and rat Wnt3A.
    表位 Central
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes Wnt3A
    同种型 IgG
    品种反应性 RatHumanMouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_149122
    Entrez基因汇总 The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region. [provided by RefSeq]
    基因符号
    • wingless-type MMTV integration site family, member 3A
    • Wnt3A
    纯化方法 Affinity Purfied
    UniProt编号
    • P56704
    UniProt汇总 FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
    SIZE: 352 amino acids; 39,365 Da
    SUBUNIT: Interacts with PORCN (By similarity).
    SUBCELLULAR LOCATION: Secreted › extracellular space › extracellular matrix.
    Tissue Specificity: Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate.
    Sequence Similarities: Belongs to the Wnt family.
    产品使用声明
    质量保证 routinely evaluated by immunoblot on rat brain lysate
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,09-162,Anti-Wnt3A Antibody

上一件merck millipore产品：merck millipore,默克密理博,ABC230,Anti-HMGA1 Antibody
下一件merck millipore产品：merck millipore,默克密理博,07-1007,Anti-IKKα Antibody


相关产品

merck millipore,默克密理博,SF-1635,IL1A; Human, Cyanine 5 RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-1635,IL1A; Human, Cyanine 5 RNA Detection Probe,SmartFlare

merck millipore,默克密理博,OP145,Anti-MDM2 (Ab-5) Mouse mAb (4B2C1.11) merck millipore,默克密理博,OP145,Anti-MDM2 (Ab-5) Mouse mAb (4B2C1.11)

merck millipore,默克密理博,SVGP01015,Sterivex-GP，0.22 µm，改良聚醚砜，射线灭菌 merck millipore,默克密理博,SVGP01015,Sterivex-GP，0.22 µm，改良聚醚砜，射线灭菌

merck millipore,默克密理博,219502,Cathepsin L Inhibitor, CAA0225 - Calbiochem merck millipore,默克密理博,219502,Cathepsin L Inhibitor, CAA0225 - Calbiochem

merck millipore,默克密理博,ABC230,Anti-HMGA1 Antibody merck millipore,默克密理博,ABC230,Anti-HMGA1 Antibody

merck millipore,默克密理博,07-1007,Anti-IKKα Antibody merck millipore,默克密理博,07-1007,Anti-IKKα Antibody

merck millipore,默克密理博,05-483,Anti-phospho-EGFR (Tyr1173) Antibody, clone 9H2 merck millipore,默克密理博,05-483,Anti-phospho-EGFR (Tyr1173) Antibody, clone 9H2

merck millipore,默克密理博,71071,pET-41 Ek/LIC Vector Kit - Novagen merck millipore,默克密理博,71071,pET-41 Ek/LIC Vector Kit - Novagen

merck millipore,默克密理博,70171,pIE1-neo DNA - Novagen merck millipore,默克密理博,70171,pIE1-neo DNA - Novagen

merck millipore,默克密理博,SF-441,miR-30c-5p; Human, Cyanine 3, RNA Detection Probe,SmartFlare merck millipore,默克密理博,SF-441,miR-30c-5p; Human, Cyanine 3, RNA Detection Probe,SmartFlare


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部