merck millipore,默克密理愽
  • merck millipore,默克密理博,219379,Cathepsin K Inhibitor II - Calbiochem

  • merck millipore,默克密理博,219379,Cathepsin K Inhibitor II - Calbiochem

    产品名称：Cathepsin K Inhibitor II - Calbiochem
    产品型号：219379
    The Cathepsin K Inhibitor II controls the biological activity of Cathepsin K. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

    merck millipore,默克密理博,219379,Cathepsin K Inhibitor II - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,219379,Cathepsin K Inhibitor II - Calbiochem

    重要规格表

    经验配方
    C₃₅H₅₁N₇O₈
    描述
    概述 A cell-permeable peptidyl bis-carbohydrazide compound that acts as a potent, selective, and reversible inhibitor of cathepsin K (Ki,app = 6 nM). Shown to completely block cathepsin K activity in primary human synovial fibroblast cultures at 1 µM. At higher concentrations, also inhibits the activities of cathepsin B and papain (Ki,app = 510 nM, 1.2 µM, respectively). Does not significantly inhibit cathepsin L.
    产品目录编号 219379
    品牌系列 Calbiochem®
    同义词 Inhibitor Boc-I, 1-(N-Benzyloxycarbonyl-leucyl)-5-(N-Boc-phenylalanyl-leucyl)carbohydrazide, Z-L-NHNHCONHNH-LF-Boc
    参考
    参考 Wang, D., et al. 2002. Biochemistry 41, 8849.
    产品信息
    具有ATP竞争性 N
    形式 Lyophilized white solid
    Hill配方 C₃₅H₅₁N₇O₈
    化学配方 C₃₅H₅₁N₇O₈
    Molar Mass 697.8
    肽序列 Boc-Phe-Leu-NHNH-CO-NHNH-Leu-Z
    可逆 Y
    生物信息
    主靶 cathepsin K
    主靶Ki 6 nM against cathepsin; 510 nM, 1.2 µM, against cathepsin B and papain, respectively
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    肽序列 Boc-Phe-Leu-NHNH-CO-NHNH-Leu-Z
    储存和货运信息
    货运代码 Blue Ice Only
    毒性 Standard Handling
    储存 -20°C
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,219379,Cathepsin K Inhibitor II - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,SLGV033RS,Millex-GV，0.22 µm，PVDF，33 mm，可 γ 射线灭菌


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