merck millipore,默克密理愽
  • merck millipore,默克密理博,218832,Caspase-3/7 Inhibitor II - CAS 775289-20-8 - Calbiochem

  • merck millipore,默克密理博,218832,Caspase-3/7 Inhibitor II - CAS 775289-20-8 - Calbiochem

    产品名称：Caspase-3/7 Inhibitor II - CAS 775289-20-8 - Calbiochem
    产品型号：218832
    The Caspase-3/7 Inhibitor II, also referenced under CAS 775289-20-8, controls the biological activity of Caspase-3/7. This small molecule/inhibitor is primarily used for Cancer applications.

    merck millipore,默克密理博,218832,Caspase-3/7 Inhibitor II - CAS 775289-20-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,218832,Caspase-3/7 Inhibitor II - CAS 775289-20-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₀H₃₁N₅O₁₀775289-20-8
    描述
    概述 A tetrapeptidyl aldehyde that acts as a potent, reversible and active site binding inhibitor of caspases-3 and -7 (IC50 = 3.2 nM and 22.6 nM, respectively) and displays ~100-fold greater selectivity over caspases-8 and -9 (IC50 = 577.6 nM and 364.7 nM, respectively). Offers protection against Camptothecin (Cat. No. 208925), and anti-Fas-mediated apoptosis in Jurkat T cells.
    产品目录编号 218832
    品牌系列 Calbiochem®
    同义词 Ac-DNLD-CHO
    参考
    参考 Yoshimori, A., et al. 2004. BMC Pharmacol. 4, 7.
    产品信息
    CAS号 775289-20-8
    具有ATP竞争性 N
    形式 White solid
    Hill配方 C₂₀H₃₁N₅O₁₀
    化学配方 C₂₀H₃₁N₅O₁₀
    Molar Mass 501.5
    肽序列 Ac-Asp-Asn-Leu-Asp-CHO
    可逆 Y
    结构配方图像
    生物信息
    主靶 caspase-3, caspase-7
    主靶IC50 3.2 nM and 22.6 nM, against caspases-3 and -7, respectively
    纯度 Single main spot with additional trace spot by TLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO or H₂O
    肽序列 Ac-Asp-Asn-Leu-Asp-CHO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,218832,Caspase-3/7 Inhibitor II - CAS 775289-20-8 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,PS1019,PhosphoDetect™ Anti-JNK1/2 (pThr¹⁸³/Tyr¹⁸⁵) Rabbit pAb
下一件merck millipore产品：merck millipore,默克密理博,7610-OP,OmniPur Sodium Acetate, Trihydrate - CAS 6131-90-4 - Calbiochem


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