merck millipore,默克密理愽
  • merck millipore,默克密理博,218714,Casein Kinase II Inhibitor IX, IQA - CAS 391670-48-7 - Calbiochem

  • merck millipore,默克密理博,218714,Casein Kinase II Inhibitor IX, IQA - CAS 391670-48-7 - Calbiochem

    产品名称：Casein Kinase II Inhibitor IX, IQA - CAS 391670-48-7 - Calbiochem
    产品型号：218714
    The Casein Kinase II Inhibitor IV, also referenced under CAS 391670-48-7, controls the biological activity of Casein Kinase II. This small molecule/inhibitor is primarily used for Phosphorylation & De More>>

    merck millipore,默克密理博,218714,Casein Kinase II Inhibitor IX, IQA - CAS 391670-48-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,218714,Casein Kinase II Inhibitor IX, IQA - CAS 391670-48-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₇H₁₂N₂O₃391670-48-7
    描述
    概述 A cell-permeable indoloquinazolinone compound that acts as a potent and selective CK2 inhibitor (IC50 = 390 nM with 100 µM ATP) in an ATP- and GTP-competitive manner (Ki = 0.17 and 0.21 µM, respectively). IQA exhibits much reduced activity against PI 3-Kα/β/γ (No inhibition at 20 µM) and 48 commonly studied protein kinases (IC50 ≥10 µM with 100 µM ATP) and is more selective than TBB (Cat. Nos. 218697 and 218708) with respect to DYRK1a (IC50 = 8 and <1 µM, respectively, with 100 µM ATP).
    产品目录编号 218714
    品牌系列 Calbiochem®
    同义词 5-Oxo-5,6-dihydroindolo[1,2-a]quinazoline-7-acetic acid
    参考
    参考 Piazza, F.A., et al. 2006. Blood 108, 1698.
    Di Maira, G., et al. 2005. Cell Death Differ. 12, 668.
    Sarno, S., et al. 2003. Biochem. J. 374, 639.
    Vangrevelinghe, E., et al. 2003. J. Med. Chem. 46, 2656.
    产品信息
    CAS号 391670-48-7
    形式 Light yellow solid
    Hill配方 C₁₇H₁₂N₂O₃
    化学配方 C₁₇H₁₂N₂O₃
    Molar Mass 292.3
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    安全信息
    S相 S: 22-24/25

    Do not breathe dust.
    Avoid contact with skin and eyes.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,218714,Casein Kinase II Inhibitor IX, IQA - CAS 391670-48-7 - Calbiochem

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