merck millipore,默克密理愽
  • merck millipore,默克密理博,204860,Complement C3b, Human

  • merck millipore,默克密理博,204860,Complement C3b, Human

    产品名称：Complement C3b, Human
    产品型号：204860


    merck millipore,默克密理博,204860,Complement C3b, Human

  • 产品介绍
  • merck millipore,默克密理博,204860,Complement C3b, Human

    描述
    概述 Native, human C3b complement component. Cleavage of the C3-α chain at peptide bond 77 by either of the complement C3 convertase enzymes results in production of C3a (M.W. 9083) and C3b (M.W. 180,000) fragments. The C3b fragment is a glycoprotein composed of the modified C3-α chain (α′) (M.W. 105,000) and the intact C3-β chain (M.W. 75,000). Nascent C3b has the transient ability to form a covalent ester bond with a variety of target surfaces. Once bound to target surfaces C3b becomes an essential subunit of both the classical and alternative pathway C5 cleaving enzymes. In addition, surface-bound C3b has opsonic and immune adherence activities which are mediated via binding to CR1 (CD35) complement receptors.
    产品目录编号 204860
    品牌系列 Calbiochem®
    参考
    参考 Wong, W.W. and Fearon, D.T. 1987. Methods Enzymol. 150, 579.
    Arnout, M.A., et al. 1981. J. Immunol. 127, 1348.
    产品信息
    形式 Liquid
    配方 In PBS, pH 7.2, filtered through a 0.22 µm filter.
    Molar Mass 180000
    生物信息
    纯度 ≥90% by SDS-PAGE
    来源 Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
    理化信息
    污染物 IgG, IgA, IgM, C5, Factor H, or Factor I: ≤trace amounts
    储存和货运信息
    货运代码 Dry Ice Only
    毒性 Standard Handling
    储存 ≤ -70°C
    避免冻结 / 解冻 Avoid freeze/thaw
    无需冷冻 No
    特殊指南 Following initial thaw, aliquot and freeze (-70°C).

    merck millipore,默克密理博,204860,Complement C3b, Human

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