merck millipore,默克密理愽
  • merck millipore,默克密理博,203401,Bleomycin Sulfate, Streptomyces verticillus - CAS 9041-93-4 - Calbiochem

  • merck millipore,默克密理博,203401,Bleomycin Sulfate, Streptomyces verticillus - CAS 9041-93-4 - Calbiochem

    产品名称：Bleomycin Sulfate, Streptomyces verticillus - CAS 9041-93-4 - Calbiochem
    产品型号：203401
    Mixture of cytotoxic glycopeptides that inhibits DNA synthesis by reacting with DNA and causing strand scission.

    merck millipore,默克密理博,203401,Bleomycin Sulfate, Streptomyces verticillus - CAS 9041-93-4 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,203401,Bleomycin Sulfate, Streptomyces verticillus - CAS 9041-93-4 - Calbiochem

    重要规格表

    CAS号
    9041-93-4
    描述
    概述 Mixture of cytotoxic glycopeptides that inhibits DNA synthesis by reacting with DNA and causing strand scission. Acts by generating hydroxyl free radicals which cleave N-glycosidic bonds and cause base elimination (mainly T) and phosphodiester bond scission. An anti-neoplastic agent. Bleomycin has been used in the treatment of squamous cell carcinomas, testicular tumors, and malignant lymphomas.
    产品目录编号 203401
    品牌系列 Calbiochem®
    参考
    参考 Tounekki, O., et al. 1994. Bull. Cancer 81, 1043.
    Chauvergne, J., et al. 1993. Bull. Cancer 80, 70.
    Ikeda, S., et al. 1991. Anal. Biochem. 192, 96.
    Hait, W.N., et al. 1990. Cancer Res. 50, 6636.
    Arkin, H., et al. 1989. Cancer Res. 49, 6556.
    Wu, J.C., et al. 1983. J. Biol. Chem. 258, 4694.
    Takita, T., et al. 1968. Antibiotics 21, 79.
    产品信息
    CAS号 9041-93-4
    形式 White to off-white solid
    吸湿 Hygroscopic
    生物信息
    生物活性 Potency: 1.5-2.0 U/mg
    纯度 ≥90% by HPLC (A₂ + B₂)
    理化信息
    溶解度 H₂O
    GHS安全信息
    RTECS EC5991990
    安全信息
    R相 R: 20/21/22-36/37/38-40-42/43

    Harmful by inhalation, in contact with skin and if swallowed.
    Irritating to eyes, respiratory system and skin.
    Limited evidence of a carcinogenic effect.
    May cause sensitization by inhalation and skin contact.
    S相 S: 22-26-36/37/39-45

    Do not breathe dust.
    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing, gloves and eye/face protection.
    In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful & Carcinogenic / Teratogenic
    储存 +2°C to +8°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short-term storage. Aqueous stock solutions (≥3 units/ml) are stable for up to 1 month at 4°C or for up to 3 months at -20°C.

    merck millipore,默克密理博,203401,Bleomycin Sulfate, Streptomyces verticillus - CAS 9041-93-4 - Calbiochem

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