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描述 产品目录编号 14-675 品牌系列 Upstate
商名 - Upstate
描述 BrSK1 Protein, active, 10 µg 概述 N-terminal 6His-tagged, recombinant, human BrSK1 amino acids 2-end 应用 应用 Active, N-terminal 6His-tagged, recombinant, human BrSK1 amino acids 2-end, for use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 expressed by baculovirus in Sf21 cells 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_032430.1
基因符号 - FLJ43009
- BRSK1
- SAD1
- KIAA1811
蛋白靶 BrSK1 纯化方法 Ni2+/NTA-agarose 靶子系列 CAMK UniProt编号 - Q8TDC3
UniProt汇总 FUNCTION: SwissProt: Q8TDC3 # Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)- induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.
COFACTOR: Magnesium.
SIZE: 794 amino acids; 86753 Da
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Nuclear in the absence of DNA damage. Translocated to the nucleus in response to UV- or MMS-induced DNA damage.
TISSUE SPECIFICITY: Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle.
SIMILARITY: SwissProt: Q8TDC3 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily. & Contains 1 protein kinase domain. & Contains 1 UBA domain.产品使用声明 质量保证 routinely evaluated by phosphorylation of CHKtide (Catalog # 12-373) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C from date of shipment 包装信息 数量 10 µg
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