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主要应用 KA 描述 产品目录编号 20-122 品牌系列 Upstate
商名 - Upstate
描述 S6 Kinase Substrate Cocktail 产品信息 演示 20mM MOPS, pH 7.2, 25mM β-glycerophosphate, 5mM EGTA, 1mM sodium orthovanadate, 1mM dithiothreitol. 应用 主要应用 - Kinase Assay
应用说明 For use in kinase assays. 生物信息 Entrez基因编号 - NM_002953.3
- NM_001006665.1
Entrez基因汇总 This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. 基因符号 - RSK
- RPS6KA1
- pp90RSK1
- HU-1
- RSK-1
- MAPKAPK1A
- p90S6K
- RSK1
UniProt编号 - Q96S38
- Q15418
- Q15349
- P51812
- O75676
- O75582
- Q9UK32
- P23443
- Q9UBS0
UniProt汇总 FUNCTION: SwissProt: Q9UK32 # Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.
COFACTOR: Magnesium (By similarity).
SIZE: 745 amino acids; 83872 Da
SUBUNIT: Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation (By similarity).
PTM: Autophosphorylated on Ser-389, as part of the activation process (By similarity).
SIMILARITY: SwissProt: Q9UK32 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 protein kinase domains.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at -20°C 包装信息 数量 1 mL
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