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merck millipore,默克密理博,196878,(±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem
产品名称：(±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem
产品型号：196878
Synthetic dihydropyridine derivative that acts as an active Ca2+ slow channel agonist in neuroendocrine, muscle, thyroid and other cell types.
merck millipore,默克密理博,196878,(±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem
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重要规格表
经验配方 CAS号 C₁₆H₁₅F₃N₂O₄ 93468-89-4 描述 概述 Synthetic dihydropyridine derivative that acts as an active Ca2+ slow channel agonist in neuroendocrine, muscle, thyroid and other cell types. Prolongs single channel open time without affecting the close time. An L-type Ca2+ channel agonist. Composed of two optical isomers. The (-)-enantiomer has strong vasoconstrictive, positive inotropic, and Ca2+ agonistic properties, whereas the (+)-enantiomer has weakly vasodilating, negative inotropic, and Ca2+ antagonistic properties. The net effect of the racemic mix is that of the negative enantiomer. Promotes β-cell proliferation/regeneration. 产品目录编号 196878 品牌系列 Calbiochem®
同义词 1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2ʹ-(trifluoromethyl)phenyl]-3-pyridinecarboxylic Acid Methyl Ester 参考 参考 Wang, W., et al. 2009. Proc. Natl. Acad. Sci. USA 106, 1427.
Weigl, L.G., et al. 2000. J. Physiol. 525 (pt. 2), 461.
Vannier, C., et al. 1995. Am. J. Physiol. 268, L201.
Bechem, M., and Hoffmann, H. 1993. Pflugers Arch. 424, 343.
Triggle, D.J., and Rompe, D. 1989. Trends Pharmacol. Sci. 10, 507.
Takasu, N., et al. 1987. Biochem. Biophys. Res. Commun. 143, 1107.
Tagliatela, M., et al. 1986. Brain Res. 381, 356.
Franckowiak, G., et al. 1985. Eur. J. Pharmacol. 114, 223.产品信息 CAS号 93468-89-4 具有ATP竞争性 N 形式 Yellow solid Hill配方 C₁₆H₁₅F₃N₂O₄ 化学配方 C₁₆H₁₅F₃N₂O₄ Molar Mass 356.3 可逆 N 结构配方图像 生物信息 主靶 L-type Ca2+ channel 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 EtOH or MeOH 安全信息 R相 R: 36/38
Irritating to eyes and skin.S相 S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Irritant
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 20 days at 4°C.
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