merck millipore,默克密理博,196419,BAPTA/AM - CAS 126150-97-8

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merck millipore,默克密理博,196419,BAPTA/AM - CAS 126150-97-8 - Calbiochem
产品名称：BAPTA/AM - CAS 126150-97-8 - Calbiochem
产品型号：196419
Membrane-permeable form of BAPTA.

merck millipore,默克密理博,196419,BAPTA/AM - CAS 126150-97-8 - Calbiochem

产品介绍

merck millipore,默克密理博,196419,BAPTA/AM - CAS 126150-97-8 - Calbiochem

重要规格表

经验配方	CAS号
C₃₄H₄₀N₂O₁₈	126150-97-8

描述
概述	Membrane-permeable form of BAPTA. Can be loaded into a wide variety of cells, where it is hydrolyzed by cytosolic esterases and is trapped intracellularly as the active chelator BAPTA. Prevents cocaine-induced ventricular fibrillations. Abolishes vitamin D₃-induced increase in intracellular Ca²⁺. Induces inactivation of protein kinase C. Also inhibits thapsigargin-induced apoptosis in rat thymocytes.
产品目录编号	196419
品牌系列	Calbiochem®
同义词	1,2-bis(o-Aminophenoxy)ethane-N,N,Nʹ,Nʹ-tetraacetic Acid Tetra(acetoxymethyl) Ester

参考
参考	Bissonnette, M., et al. 1994. Am. J. Physiol. 267, G465. Jiang, S., et al. 1994. Exp. Cell Res. 212, 84. Billman, G.E. 1993. Am. J. Physiol. 265, H1529. Dieter, P., et al. 1993. Biol. Chem. Hoppe Seyler 374, 171. Harrison, S.M., and Bers, D.M. 1987. Biochim. Biophys. Acta 925, 133. Harrison, S.M., and Bers, D.M. 1987. J. Biophys. 51, 102A. Marban, E., et al. 1986. J. Clin. Invest. 78, 1185. Tsien, R.Y. 1981. Nature 290, 527. Tsien, R.Y. 1980. Biochemistry 19, 2396.

参考

Bissonnette, M., et al. 1994. Am. J. Physiol. 267, G465.
Jiang, S., et al. 1994. Exp. Cell Res. 212, 84.
Billman, G.E. 1993. Am. J. Physiol. 265, H1529.
Dieter, P., et al. 1993. Biol. Chem. Hoppe Seyler 374, 171.
Harrison, S.M., and Bers, D.M. 1987. Biochim. Biophys. Acta 925, 133.
Harrison, S.M., and Bers, D.M. 1987. J. Biophys. 51, 102A.
Marban, E., et al. 1986. J. Clin. Invest. 78, 1185.
Tsien, R.Y. 1981. Nature 290, 527.
Tsien, R.Y. 1980. Biochemistry 19, 2396.

产品信息
CAS号	126150-97-8
形式	Light yellow solid
Hill配方	C₃₄H₄₀N₂O₁₈
化学配方	C₃₄H₄₀N₂O₁₈
Molar Mass	764.7
结构配方图像

生物信息
纯度	≥90% by TLC

理化信息
溶解度	DMSO

安全信息
R相	R: 36/37/38 Irritating to eyes, respiratory system and skin.
S相	S: 26-36 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Irritant
储存	-20°C
避光	Protect from light
无需冷冻	No
特殊指南	Following reconstitution, aliquot, purge with inert gas and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.