merck millipore,默克密理愽
  • merck millipore,默克密理博,14-748M,Src (T341M) Protein, active, 250 µg

  • merck millipore,默克密理博,14-748M,Src (T341M) Protein, active, 250 µg

    产品名称：Src (T341M) Protein, active, 250 µg
    产品型号：14-748M
    Active, N-terminal 6His-tagged, recombinant, full-length human Src, containing the T341M mutation. For use in Kinase Assays.

    merck millipore,默克密理博,14-748M,Src (T341M) Protein, active, 250 µg

  • 产品介绍
  • merck millipore,默克密理博,14-748M,Src (T341M) Protein, active, 250 µg

    描述
    产品目录编号 14-748M
    品牌系列 Upstate
    商名
    • Upstate
    描述 Src (T341M) Protein, active, 250 µg
    概述 N-terminal 6His-tagged, recombinant, full-length human Src, containing the T341M mutation.
    应用
    应用 Active, N-terminal 6His-tagged, recombinant, full-length human Src, containing the T341M mutation. For use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 Expressed by baculovirus in Sf21 insect cells.
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_198291.1
    • NM_005417.3
    Entrez基因汇总 This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
    基因符号
    • pp60c-src
    • SRC
    • c-src
    • p60-Src
    • SRC1
    • c-SRC
    • ASV
    蛋白靶 Src
    纯化方法 Ni2+/NTA-agarose
    靶子系列 TK
    UniProt编号
    • P12931
    UniProt汇总 SIZE: 536 amino acids; 59835 Da
    SUBUNIT: Interacts with DDEF1/ASAP1 via its SH3 domain. Interacts with CCPG1 (By similarity). Interacts with CDCP1, PELP1, TGFB1I1 and TOM1L2.
    PTM: Phosphorylated on Tyr-530 by c-Src kinase (CSK). The phosphorylated form is termed pp60c-src. The phosphorylated tail interacts with the SH2 domain thereby repressing kinase activity.
    SIMILARITY: SwissProt: P12931 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C from date of shipment.
    包装信息
    数量 250 µg
    包装 Also available in 10 μg size (cat#14-748) and in bulk (cat# 14-748-K).

    merck millipore,默克密理博,14-748M,Src (T341M) Protein, active, 250 µg

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