merck millipore,默克密理愽
  • merck millipore,默克密理博,14-646,TCPTP Protein, 10 µg

  • merck millipore,默克密理博,14-646,TCPTP Protein, 10 µg

    产品名称：TCPTP Protein, 10 µg
    产品型号：14-646
    Un-tagged, recombinant, human TCPTP, amino acids 1-341. For use in Phosphatase Assays.

    merck millipore,默克密理博,14-646,TCPTP Protein, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-646,TCPTP Protein, 10 µg

    描述
    产品目录编号 14-646
    品牌系列 Upstate
    商名
    • Upstate
    描述 TCPTP Protein, 10 µg
    概述 Un-tagged, recombinant, human TCPTP, amino acids 1-341.
    应用
    应用 Un-tagged, recombinant, human TCPTP, amino acids 1-341. For use in Phosphatase Assays.
    主要应用
    • Phosphatase Assay
    生物信息
    来源 Human TCPTP, expressed in E. coli cells.
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_080423.1
    • NM_002828.2
    • NM_080422.1
    Entrez基因汇总 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Three alternatively spliced variants of this gene, which encode isoforms differing at their extreme C-termini, have been described. The different C-termini are thought to determine the substrate specificity, as well as the cellular localization of the isoforms. Two highly related but distinctly processed pseudogenes that localize to distinct chromosomes have been reported.
    基因符号
    • PTPT
    • PTPN2
    • TCELLPTP
    • TCPTP
    • TC-PTP
    蛋白靶 TCPTP
    纯化方法 Glutathione agarose affinity chromatography
    靶子系列 Tyr phosphatase
    UniProt编号
    • P17706
    UniProt汇总 SIZE: 415 amino acids; 48528 Da
    SUBUNIT: Interacts with FAM82C/PTPIP51.
    SUBCELLULAR LOCATION: Cytoplasm.
    TISSUE SPECIFICITY: PTPA isoform is probably the major PTP expressed in human tissues. PTPB isoform was found in T-cells and in placenta.
    SIMILARITY: SwissProt: P17706 ## Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily. & Contains 1 tyrosine-protein phosphatase domain.
    产品使用声明
    质量保证 Routinely evaluated by dephosphorylation of DiFMUP.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C
    包装信息
    数量 10 µg

    merck millipore,默克密理博,14-646,TCPTP Protein, 10 µg

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