merck millipore,默克密理愽
  • merck millipore,默克密理博,14-612,RIPK2 Protein, active, 10 µg

  • merck millipore,默克密理博,14-612,RIPK2 Protein, active, 10 µg

    产品名称：RIPK2 Protein, active, 10 µg
    产品型号：14-612
    Active, human RIPK2, amino acids 1-299, for use in Kinase Assays.

    merck millipore,默克密理博,14-612,RIPK2 Protein, active, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-612,RIPK2 Protein, active, 10 µg

    描述
    产品目录编号 14-612
    品牌系列 Upstate
    商名
    • Upstate
    描述 RIPK2 Protein, active, 10 µg
    概述 human RIPK2, amino acids 1-299
    应用
    应用 Active, human RIPK2, amino acids 1-299, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 N-terminal His6-tagged, recombinant, human RIPK2 expressed by baculovirus in Sf21 insect cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_003821.5
    Entrez基因汇总 This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
    基因符号
    • RIP-2
    • RIPK2
    • RIP2
    • GIG30
    • RICK
    • CARDIAK
    • CARD3
    • CCK
    蛋白靶 RIPK2
    纯化方法 Ni2+/NTA-agarose
    靶子系列 TKL
    UniProt编号
    • O43353
    UniProt汇总 FUNCTION: SwissProt: O43353 # Activates pro-caspase-1 and pro-caspase-8. Potentiates CASP8-mediated apoptosis. Activates NF-kappa-B.
    SIZE: 540 amino acids; 61195 Da
    SUBUNIT: Binds to CFLAR/CLARP and CASP1 via their CARD domains. Binds to BIRC3/c-IAP1 and BIRC2/c-IAP2, TRAF1, TRAF2, TRAF5 and TRAF6. May be a component of both the TNFRSF1A and TNRFSF5/CD40 receptor complex.
    SUBCELLULAR LOCATION: Cytoplasm (Probable).
    TISSUE SPECIFICITY: Detected in heart, brain, placenta, lung, peripheral blood leukocytes, spleen, kidney, testis, prostate, pancreas and lymph node.
    PTM: Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.
    SIMILARITY: SwissProt: O43353 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 CARD domain. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of MBP
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C
    包装信息
    数量 10 µg

    merck millipore,默克密理博,14-612,RIPK2 Protein, active, 10 µg

上一件merck millipore产品：merck millipore,默克密理博,01-125,NGF 2.5S Protein, mouse
下一件merck millipore产品：merck millipore,默克密理博,SF-1554,TNFSF10; Human, Cyanine 5 RNA Detection Probe,SmartFlare


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